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anti-KRT2 antibody :: Rabbit Keratin 2 (KRT2) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2003662 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Keratin 2 (KRT2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Keratin 2 (KRT2)

 Product Gene Name   

anti-KRT2 antibody

[Similar Products]
 Matching Pairs    Antibody: Keratin 2 (KRT2) (MBS2003662)
Antigen: Keratin 2 (KRT2) (MBS2012323)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
APC-CY7 Conjugated Antibody: Keratin 2 (KRT2) (MBS2043050)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
PE Conjugated Antibody: Keratin 2 (KRT2) (MBS2043052)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
APC-CY7 Conjugated Antibody: Keratin 2 (KRT2) (MBS2043054)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
Cy3 Conjugated Antibody: Keratin 2 (KRT2) (MBS2043056)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
FITC Conjugated Antibody: Keratin 2 (KRT2) (MBS2043058)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
HRP Conjugated Antibody: Keratin 2 (KRT2) (MBS2043060)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Keratin 2 (KRT2) (MBS2003662)
Biotin Conjugated Antibody: Keratin 2 (KRT2) (MBS2092067)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF-IAE VQSQYEIIAH KSKAESEELY HSKANEELQV TAVKHGDSLK EIKMEISELN RTIQRLQGEI SHVKKQCKGV QDSIADAEQR GEHAIKDARG KLTDLEEALQ QGRENLARLL RDYQELMNVK LALDVEIATY RKLLEGE
 3D Structure    ModBase 3D Structure for Q6IG02
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
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 Specificity    The antibody is a rabbit polyclonal antibody raised against KRT2. It has been selected for its ability to recognize KRT2 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant KRT2 (Ile368~Glu507) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2043054
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-KRT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-KRT2 antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-KRT2 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-KRT2 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) Knockout Verification of anti-KRT2 antibody    Knockout Verification: Lane 1: Wild-type A431 cell lysate
Lane 2: KRT2 knockout A431 cell lysate
Predicted MW: 69kDa ;Observed MW: 69kDa;Primary Ab: 1ug/ml Rabbit Anti-Rat KRT2 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;
anti-KRT2 antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-KRT2 antibody    Western Blot; Sample: Recombinant protein.
anti-KRT2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-KRT2 antibody    DAB staining on IHC-P; Samples: Rat Cerebrum Tissue)
anti-KRT2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for KRT2. It may not necessarily be applicable to this product.
 NCBI GI #    57114290
 NCBI GeneID    406228
 NCBI Accession #    NP_001008899.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001008899.1 [Other Products]
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 UniProt Primary Accession #    Q6IG02 [Other Products]
 UniProt Related Accession #    Q6IG02 [Other Products]
 Molecular Weight    69,127 Da
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 NCBI Official Full Name    keratin, type II cytoskeletal 2 epidermal
 NCBI Official Synonym Full Names    keratin 2
 NCBI Official Symbol    Krt2 [Similar Products]
 NCBI Official Synonym Symbols   
Kb2; CK 2e
[Similar Products]
 NCBI Protein Information    keratin, type II cytoskeletal 2 epidermal
 UniProt Protein Name    Keratin, type II cytoskeletal 2 epidermal
 UniProt Synonym Protein Names   
Cytokeratin-2e; CK-2e; Epithelial keratin-2e; Keratin-2 epidermis; Keratin-2e; K2e; Type-II keratin Kb2
 Protein Family    Keratin
 UniProt Gene Name    Krt2 [Similar Products]
 UniProt Synonym Gene Names    CK-2e; K2e [Similar Products]
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 UniProt Comments for KRT2    K2: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: cornified envelope; extracellular space; keratin filament; membrane; nucleus

Molecular Function: cytoskeletal protein binding; structural constituent of epidermis; structural molecule activity

Biological Process: epidermis development; intermediate filament organization; keratinization; keratinocyte activation; keratinocyte migration; keratinocyte proliferation; peptide cross-linking
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KRT2 antibodyDiseases associated with anti-KRT2 antibody
 Reference Product  PubMed Publications
 Krt7 antibody  >9 publications with KRT2 and Krt7
 Krt10 antibody  >9 publications with KRT2 and Krt10
 Krt8 antibody  >3 publications with KRT2 and Krt8
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >21 publications with KRT2 and Congenital Abnormalities
 Ichthyosis Bullosa of Siemens Antibodies  >13 publications with KRT2 and Ichthyosis Bullosa of Siemens
 Liver Diseases Antibodies  >5 publications with KRT2 and Liver Diseases
 Hyperplasia Antibodies  >3 publications with KRT2 and Hyperplasia
 Kidney Diseases Antibodies  >2 publications with KRT2 and Kidney Diseases
 Liver Neoplasms Antibodies  >2 publications with KRT2 and Liver Neoplasms
 Necrosis Antibodies  >2 publications with KRT2 and Necrosis
 Inflammation Antibodies  >2 publications with KRT2 and Inflammation
 Immune System Diseases Antibodies  >2 publications with KRT2 and Immune System Diseases
 Drug-Induced Liver Injury Antibodies  >2 publications with KRT2 and Drug-Induced Liver Injury
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