CAF31522.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,417 Da
NCBI Official Full Name
keratin 3
NCBI Official Synonym Full Names
keratin 3
NCBI Official Synonym Symbols
NCBI Protein Information
keratin, type II cytoskeletal 3
UniProt Protein Name
Keratin, type II cytoskeletal 3
UniProt Synonym Protein Names
65 kDa cytokeratin; Cytokeratin-3; CK-3; Keratin-3; K3; Type-II keratin Kb3
UniProt Synonym Gene Names
NCBI Summary for KRT3
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT3
K3: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K12.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: keratin filament
Molecular Function: structural molecule activity
Biological Process: epithelial cell differentiation; intermediate filament cytoskeleton organization and biogenesis
Disease: Corneal Dystrophy, Meesmann
Research Articles on KRT3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-KRT3 antibody
Diseases associated with anti-KRT3 antibody
Organs/Tissues associated with anti-KRT3 antibody
|