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anti-KRT7 antibody :: Rabbit anti-Human Keratin 7 (KRT7) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2002756 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Western Blot (WB)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $335 +1 FREE 8GB USB
1 mg  /  $795 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Keratin 7 (KRT7), Polyclonal Antibody

★Popular Item★
 Also Known As   

Biotin-Linked Antibody to Keratin 7 (KRT7)

 Product Gene Name   

anti-KRT7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (52626954..52642709). Location: 12q13.13
 OMIM    148059
 3D Structure    ModBase 3D Structure for P08729
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against KRT7 conjugated to biotin. It has been selected for its ability to recognize KRT7 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography.
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Antibody labeling
 Traits    Liquid
 Immunogen    RPA556Hu01-Recombinant Keratin 7 (KRT7)
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2006940
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-KRT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-KRT7 antibody    Biotin Antibody
 Applications Tested/Suitable for anti-KRT7 antibody   

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

 Application Notes for anti-KRT7 antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-KRT7 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-KRT7 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for KRT7. It may not necessarily be applicable to this product.
 NCBI GI #    67782365
 NCBI GeneID    3855
 NCBI Accession #    NP_005547.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005556.3 [Other Products]
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 UniProt Primary Accession #    P08729 [Other Products]
 UniProt Secondary Accession #    Q92676; Q9BUD8; Q9Y3R7 [Other Products]
 UniProt Related Accession #    P08729 [Other Products]
 Molecular Weight    51,386 Da
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 NCBI Official Full Name    keratin, type II cytoskeletal 7
 NCBI Official Synonym Full Names    keratin 7
 NCBI Official Symbol    KRT7 [Similar Products]
 NCBI Official Synonym Symbols   
K7; CK7; SCL; K2C7
[Similar Products]
 NCBI Protein Information    keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7
 UniProt Protein Name    Keratin, type II cytoskeletal 7
 UniProt Synonym Protein Names   
Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
 Protein Family    Keratin
 UniProt Gene Name    KRT7 [Similar Products]
 UniProt Synonym Gene Names    SCL; CK-7; K7 [Similar Products]
 UniProt Entry Name    K2C7_HUMAN
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 NCBI Summary for KRT7    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KRT7    K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: viral reproduction
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 Research Articles on KRT7    1. CK7 and Cam 5.2 expression may occur in SCC. A panel including Ber-Ep4 is advisable for immunohistochemical differentiation of EPD from SCC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KRT7 antibodyPathways associated with anti-KRT7 antibody
 Reference Product  PubMed Publications
 MUC2 antibody  >18 publications with KRT7 and MUC2
 CDX2 antibody  >17 publications with KRT7 and CDX2
 MUC1 antibody  >11 publications with KRT7 and MUC1
 CALB2 antibody  >5 publications with KRT7 and CALB2
 PIP antibody  >5 publications with KRT7 and PIP
 EIF3A antibody  >1 publications with KRT7 and EIF3A
 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
Diseases associated with anti-KRT7 antibodyOrgans/Tissues associated with anti-KRT7 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >367 publications with KRT7 and Neoplasms
 Liver Diseases Antibodies  >60 publications with KRT7 and Liver Diseases
 Lung Neoplasms Antibodies  >57 publications with KRT7 and Lung Neoplasms
 Neoplasm Metastasis Antibodies  >50 publications with KRT7 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >50 publications with KRT7 and Breast Neoplasms
 Skin Diseases Antibodies  >48 publications with KRT7 and Skin Diseases
 Liver Neoplasms Antibodies  >43 publications with KRT7 and Liver Neoplasms
 Kidney Diseases Antibodies  >40 publications with KRT7 and Kidney Diseases
 Carcinoma, Renal Cell Antibodies  >35 publications with KRT7 and Carcinoma, Renal Cell
 Urinary Bladder Neoplasms Antibodies  >34 publications with KRT7 and Urinary Bladder Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >60 publications with KRT7 and Lung
 Stomach Antibodies  >45 publications with KRT7 and Stomach
 Ovary Antibodies  >38 publications with KRT7 and Ovary
 Thyroid Antibodies  >36 publications with KRT7 and Thyroid
 Intestine Antibodies  >34 publications with KRT7 and Intestine
 Placenta Antibodies  >29 publications with KRT7 and Placenta
 Lymph Node Antibodies  >28 publications with KRT7 and Lymph Node
 Prostate Antibodies  >20 publications with KRT7 and Prostate
 Vascular Antibodies  >17 publications with KRT7 and Vascular
 Uterus Antibodies  >13 publications with KRT7 and Uterus
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