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anti-Ku80 antibody :: Rabbit Ku80 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS536003 anti-Ku80 antibody
Unit / Price
0.1 mg  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ku80, Polyclonal Antibody

 Also Known As   

Ku80 antibody

 Product Synonym Names    Polyclonal Ku80; Anti-Ku80; Heterodimer of Ku80 subunits; Ku80; Ku -80; Ku 80
 Product Gene Name   

anti-Ku80 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9I7M8
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Hamster, Human, Mouse, Rat
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 Purity/Purification    Ku80 antibody was purified by affinity chromatography.
 Form/Format    Affinity purified IgG supplied in PBS with 0.02% NaN3.
 Concentration    1.0 mg/ml (lot specific)
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 Biological Significance    The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Immunogen    Ku80 antibody was raised in rabbit using residues 419-440 [LVYVQLPFMEDLRQYMFSSLKN] of the 80 kDa Ku80 protein as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-Ku80 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-Ku80 antibody

   Affinity purified Rabbit polyclonal Ku80 antibody
 Product Categories/Family for anti-Ku80 antibody    DNA & RNA ; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-Ku80 antibody   

Western Blot (WB)

 Application Notes for anti-Ku80 antibody    WB: 1:500-1:1,000
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NCBI/Uniprot data below describe general gene information for Ku80. It may not necessarily be applicable to this product.
 NCBI GI #    24584494
 NCBI GeneID    34930
 NCBI Accession #    NP_609767.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_135923.2 [Other Products]
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 UniProt Primary Accession #    Q9I7M8 [Other Products]
 UniProt Related Accession #    Q9I7M8 [Other Products]
 Molecular Weight    79,823 Da
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 NCBI Official Full Name    Ku80
 NCBI Official Symbol    Ku80 [Similar Products]
 NCBI Official Synonym Symbols   
BG:DS09217.6; CG18801; DmelCG18801; DmKu80; Ku; ku80; KU80
[Similar Products]
 NCBI Protein Information    CG18801 gene product from transcript CG18801-RA
 UniProt Protein Name    ATP-dependent DNA helicase II subunit 2
 Protein Family    ATP-dependent DNA helicase
 UniProt Gene Name    Ku80 [Similar Products]
 UniProt Entry Name    Q9I7M8_DROME
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 UniProt Comments for Ku80    Single-stranded DNA-dependent ATP-dependent helicase.
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 Research Articles on Ku80    1. specific regulation of ku80 expression by UTX
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Ku80 antibodyPathways associated with anti-Ku80 antibody
 Reference Product  PubMed Publications
 Parp antibody  >36 publications with Ku80 and Parp
 mre11 antibody  >29 publications with Ku80 and mre11
 Lig4 antibody  >22 publications with Ku80 and Lig4
 Blm antibody  >7 publications with Ku80 and Blm
 Products by Pathway  Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Double-Strand Break Repair Pathway antibodies  Double-Strand Break Repair Pathway Diagram
 Non-homologous End-joining Pathway antibodies  Non-homologous End-joining Pathway Diagram
 Non-homologous End-joining Pathway antibodies  Non-homologous End-joining Pathway Diagram
 Nonhomologous End-joining (NHEJ) Pathway antibodies  Nonhomologous End-joining (NHEJ) Pathway Diagram
Diseases associated with anti-Ku80 antibodyOrgans/Tissues associated with anti-Ku80 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >61 publications with Ku80 and Carcinoma
 Lung Diseases Antibodies  >17 publications with Ku80 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >12 publications with Ku80 and Cell Transformation, Neoplastic
 Melanoma Antibodies  >9 publications with Ku80 and Melanoma
 Inflammation Antibodies  >8 publications with Ku80 and Inflammation
 Prostatic Neoplasms Antibodies  >6 publications with Ku80 and Prostatic Neoplasms
 Necrosis Antibodies  >6 publications with Ku80 and Necrosis
 Urinary Bladder Neoplasms Antibodies  >3 publications with Ku80 and Urinary Bladder Neoplasms
 Aneuploidy Antibodies  >3 publications with Ku80 and Aneuploidy
 Bacterial Infections Antibodies  >2 publications with Ku80 and Bacterial Infections
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >7 publications with Ku80 and Embryonic Tissue
 Testis Antibodies  >5 publications with Ku80 and Testis
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