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anti-KCNC4 antibody :: Rabbit Kv3.4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS821441 anti-KCNC4 antibody
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kv3.4 (KCNC4), Polyclonal Antibody

 Also Known As   

Anti-Kv3.4 Antibody

 Product Synonym Names    Potassium voltage-gated channel subfamily C member 4; KSHIIIC; Voltage-gated potassium channel subunit Kv3.4
 Product Gene Name   

anti-KCNC4 antibody

[Similar Products]
 Antibody/Peptide Pairs    Kv3.4 peptide (MBS823934) is used for blocking the activity of Kv3.4 antibody (MBS821441)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176265
 3D Structure    ModBase 3D Structure for Q03721
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of Kv3.4 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Kv3.4. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-KCNC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-KCNC4 antibody

   Rabbit polyclonal antibody to Kv3.4
 Applications Tested/Suitable for anti-KCNC4 antibody   

Western Blot (WB)

 Application Notes for anti-KCNC4 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-KCNC4 antibody    anti-KCNC4 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for KCNC4. It may not necessarily be applicable to this product.
 NCBI GI #    88758576
 NCBI GeneID    3749
 NCBI Accession #    NP_001034663.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039574.2 [Other Products]
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 UniProt Primary Accession #    Q03721 [Other Products]
 UniProt Secondary Accession #    Q3MIM4; Q5TBI6 [Other Products]
 UniProt Related Accession #    Q03721 [Other Products]
 Molecular Weight    68,824 Da
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 NCBI Official Full Name    potassium voltage-gated channel subfamily C member 4 isoform c
 NCBI Official Synonym Full Names    potassium voltage-gated channel, Shaw-related subfamily, member 4
 NCBI Official Symbol    KCNC4 [Similar Products]
 NCBI Official Synonym Symbols   
KV3.4; C1orf30; KSHIIIC; HKSHIIIC
[Similar Products]
 NCBI Protein Information    potassium voltage-gated channel subfamily C member 4; K+ channel subunit; voltage-gated potassium channel subunit KV3.4
 UniProt Protein Name    Potassium voltage-gated channel subfamily C member 4
 UniProt Synonym Protein Names   
KSHIIIC; Voltage-gated potassium channel subunit Kv3.4
 Protein Family    Potassium voltage-gated channel subfamily
 UniProt Gene Name    KCNC4 [Similar Products]
 UniProt Entry Name    KCNC4_HUMAN
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 NCBI Summary for KCNC4    The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
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 UniProt Comments for KCNC4    Kv3.4: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.4/KCNC4 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p21

Cellular Component: voltage-gated potassium channel complex; integral to membrane; plasma membrane; nerve terminal; neuromuscular junction

Molecular Function: voltage-gated potassium channel activity; potassium channel activity; delayed rectifier potassium channel activity

Biological Process: synaptic transmission; regulation of neurotransmitter secretion; protein homooligomerization; potassium ion transport
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 Research Articles on KCNC4    1. Ionizing radiation-induced G2/M arrest was preceded by activation of Kv3.4-like voltage-gated potassium channels.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KCNC4 antibodyPathways associated with anti-KCNC4 antibody
 Reference Product  PubMed Publications
 KCNE3 antibody  >5 publications with KCNC4 and KCNE3
 KCNQ1 antibody  >2 publications with KCNC4 and KCNQ1
 KCNH6 antibody  >2 publications with KCNC4 and KCNH6
 Products by Pathway  Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Potassium Channels Pathway antibodies  Potassium Channels Pathway Diagram
 Voltage Gated Potassium Channels Pathway antibodies  Voltage Gated Potassium Channels Pathway Diagram
Diseases associated with anti-KCNC4 antibodyOrgans/Tissues associated with anti-KCNC4 antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >4 publications with KCNC4 and Disease Models, Animal
 Mental Disorders Antibodies  >2 publications with KCNC4 and Mental Disorders
 Dementia Antibodies  >2 publications with KCNC4 and Dementia
 Carcinoma Antibodies  >2 publications with KCNC4 and Carcinoma
 Seizures Antibodies  >1 publications with KCNC4 and Seizures
 Acidosis Antibodies  >1 publications with KCNC4 and Acidosis
 Arrhythmias, Cardiac Antibodies  >1 publications with KCNC4 and Arrhythmias, Cardiac
 Alcoholism Antibodies  >1 publications with KCNC4 and Alcoholism
 Epilepsy, Temporal Lobe Antibodies  >1 publications with KCNC4 and Epilepsy, Temporal Lobe
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >11 publications with KCNC4 and Muscle
 Brain Antibodies  >8 publications with KCNC4 and Brain
 Blood Antibodies  >5 publications with KCNC4 and Blood
 Heart Antibodies  >3 publications with KCNC4 and Heart
 Uterus Antibodies  >2 publications with KCNC4 and Uterus
 Stomach Antibodies  >1 publications with KCNC4 and Stomach
 Thymus Antibodies  >1 publications with KCNC4 and Thymus
 Ovary Antibodies  >1 publications with KCNC4 and Ovary
 Eye Antibodies  >1 publications with KCNC4 and Eye
 Mouth Antibodies  >1 publications with KCNC4 and Mouth
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