anti-AASDHPPT antibody :: Rabbit anti-Human L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Polyclonal Antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Immunogen
Recombinant human L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase protein(1-309aa)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130931
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-AASDHPPT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-AASDHPPT antibody
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.
This protein is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
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Applications Tested/Suitable for
anti-AASDHPPT antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Western blot
All lanes: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase antibody at 2ug/ml+HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 36,16 kDa
Observed band size: 36 kDa
Immunohistochemistry (IHC) of
anti-AASDHPPT antibody
Immunohistochemistry of paraffin-embedded human testis using MBS7004302 at dilution 1:100
NCBI/Uniprot data below describe general gene information for
AASDHPPT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056238.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,574 Da
NCBI Official Full Name
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
NCBI Official Synonym Full Names
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
NCBI Official Synonym Symbols
ACPS; LYS2; LYS5; CGI-80; AASD-PPT [Similar Products]
NCBI Protein Information
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
UniProt Protein Name
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
UniProt Synonym Protein Names
4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT; LYS5 ortholog
UniProt Synonym Gene Names
UniProt Entry Name
ADPPT_HUMAN
NCBI Summary for AASDHPPT
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
UniProt Comments for AASDHPPT
AASDHPPT: Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN. Belongs to the P-Pant transferase superfamily. AcpS family.
Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - lysine biosynthesis; EC 2.7.8.-; Transferase
Chromosomal Location of Human Ortholog: 11q22
Cellular Component: cytosol
Molecular Function: magnesium ion binding; phosphopantetheinyltransferase activity; protein binding
Biological Process: lysine biosynthetic process via aminoadipic acid; pantothenate metabolic process; peptidyl-serine phosphopantetheinylation; vitamin metabolic process; water-soluble vitamin metabolic process
Research Articles on AASDHPPT
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-AASDHPPT antibody
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