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anti-LAG3 antibody :: Rabbit anti-Human LAG3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS127046
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LAG3, Polyclonal Antibody

 Also Known As   


 Product Gene Name   

anti-LAG3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    153337
 3D Structure    ModBase 3D Structure for P18627
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Species    Human
 Route    Synthetic Peptide
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 Other Notes    Small volumes of anti-LAG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-LAG3 antibody    Polyclonal
 Applications Tested/Suitable for anti-LAG3 antibody   

Western Blot (WB)

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 Western Blot (WB) of anti-LAG3 antibody    Western blot analysis of extracts of various cell lines, using LAG3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
anti-LAG3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for LAG3. It may not necessarily be applicable to this product.
 NCBI GI #    251757512
 NCBI GeneID    3902
 NCBI Accession #    P18627.5 [Other Products]
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 UniProt Primary Accession #    P18627 [Other Products]
 UniProt Secondary Accession #    Q7Z643; A8K7T9 [Other Products]
 UniProt Related Accession #    P18627 [Other Products]
 Molecular Weight    525
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 NCBI Official Full Name    Lymphocyte activation gene 3 protein
 NCBI Official Synonym Full Names    lymphocyte-activation gene 3
 NCBI Official Symbol    LAG3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    lymphocyte activation gene 3 protein
 UniProt Protein Name    Lymphocyte activation gene 3 protein
 UniProt Synonym Protein Names   
Protein FDC; CD_antigen: CD223
 Protein Family    Lymphocyte activation gene 3 protein
 UniProt Gene Name    LAG3 [Similar Products]
 UniProt Synonym Gene Names    FDC; LAG-3 [Similar Products]
 UniProt Entry Name    LAG3_HUMAN
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 NCBI Summary for LAG3    Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LAG3    LAG3: Involved in lymphocyte activation. Binds to HLA class-II antigens.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.32

Cellular Component: integral to membrane; external side of plasma membrane

Molecular Function: transmembrane receptor activity; antigen binding; MHC class II protein binding

Biological Process: cell surface receptor linked signal transduction; negative regulation of interleukin-2 biosynthetic process; positive regulation of natural killer cell mediated cytotoxicity; negative regulation of T cell activation
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 Research Articles on LAG3    1. LAG-3 trafficking from lysosomal compartments to the cell surface is dependent on the cytoplasmic domain through protein kinase C signaling in activated T cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LAG3 antibodyDiseases associated with anti-LAG3 antibody
 Reference Product  PubMed Publications
 CD4 antibody  >35 publications with LAG3 and CD4
 FOXP3 antibody  >23 publications with LAG3 and FOXP3
 CTLA4 antibody  >12 publications with LAG3 and CTLA4
 PDCD1 antibody  >3 publications with LAG3 and PDCD1
 GZMB antibody  >2 publications with LAG3 and GZMB
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11 publications with LAG3 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with LAG3 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >3 publications with LAG3 and Neoplasms, Experimental
 Lymphoma Antibodies  >3 publications with LAG3 and Lymphoma
 Necrosis Antibodies  >3 publications with LAG3 and Necrosis
 Carcinoma Antibodies  >3 publications with LAG3 and Carcinoma
 Immunologic Deficiency Syndromes Antibodies  >2 publications with LAG3 and Immunologic Deficiency Syndromes
 Lung Neoplasms Antibodies  >2 publications with LAG3 and Lung Neoplasms
 Carcinoma, Squamous Cell Antibodies  >2 publications with LAG3 and Carcinoma, Squamous Cell
 Heart Diseases Antibodies  >1 publications with LAG3 and Heart Diseases
Organs/Tissues associated with anti-LAG3 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with LAG3 and Blood
 Spleen Antibodies  >7 publications with LAG3 and Spleen
 Intestine Antibodies  >2 publications with LAG3 and Intestine
 Uterus Antibodies  >1 publications with LAG3 and Uterus
 Brain Antibodies  >1 publications with LAG3 and Brain
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