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anti-LASP1 antibody :: Goat LASP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421007
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LASP1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-LASP1 (N Terminus) Antibody

 Product Synonym Names    Goat Anti-LASP1 (internal region) Antibody; LASP1; LIM and SH3 protein 1; MLN50; Lasp-1; LIM and SH3 protein; LASP1 antibody; LIM and SH3 protein 1 antibody; MLN50 antibody; Lasp-1 antibody; LIM and SH3 protein antibody; LASP1 (N Terminus)
 Product Gene Name   

anti-LASP1 antibody

[Similar Products]
 Antibody/Peptide Pairs    LASP1 peptide (MBS428069) is used for blocking the activity of LASP1 antibody (MBS421007)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    NPNCARCGKI VYP
 OMIM    602920
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence NPNCARCGKIVYP, from the N Terminus of the protein sequence according to NP_006139.1.
 Epitope    N Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-LASP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-LASP1 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-LASP1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 35kDa band observed in Human Brain (Cerebellum) and Human Colon, Duodenum, Liver and Pancreas lysates (calculated MW of 29.7kDa according to NP_006139.1). Recommended concentration: 1-3ug/ml.
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 Western Blot (WB) of anti-LASP1 antibody    (1ug/ml) staining of Human Cerebellum (A), Colon (B) and Duodenum (C) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
anti-LASP1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for LASP1. It may not necessarily be applicable to this product.
 NCBI GI #    5453710
 NCBI GeneID    3927
 NCBI Accession #    NP_006139.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006148.3 [Other Products]
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 UniProt Secondary Accession #    Q96ED2; Q96IG0; B4DGQ0 [Other Products]
 UniProt Related Accession #    Q14847 [Other Products]
 Molecular Weight    23,181 Da
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 NCBI Official Full Name    LIM and SH3 domain protein 1 isoform a
 NCBI Official Synonym Full Names    LIM and SH3 protein 1
 NCBI Official Symbol    LASP1 [Similar Products]
 NCBI Official Synonym Symbols   
MLN50; Lasp-1
[Similar Products]
 NCBI Protein Information    LIM and SH3 domain protein 1
 UniProt Protein Name    LIM and SH3 domain protein 1
 UniProt Synonym Protein Names   
Metastatic lymph node gene 50 protein; MLN 50
 Protein Family    LIM and SH3 domain protein
 UniProt Gene Name    LASP1 [Similar Products]
 UniProt Synonym Gene Names    MLN50; LASP-1; MLN 50 [Similar Products]
 UniProt Entry Name    LASP1_HUMAN
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 NCBI Summary for LASP1    This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]
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 UniProt Comments for LASP1    Lasp-1: a member of the LIM protein subfamily, characterized by a LIM motif and SH3 domain. Functions as an actin-binding protein, possibly in cytoskeletal organization.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 17q11-q21.3

Cellular Component: cortical actin cytoskeleton; focal adhesion

Molecular Function: actin filament binding; ion transmembrane transporter activity; protein binding; SH3/SH2 adaptor activity; zinc ion binding

Biological Process: ion transport; positive regulation of signal transduction
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 Research Articles on LASP1    1. Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin in the physiological process of membrane constriction and melanosome vesicle release.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LASP1 antibodyDiseases associated with anti-LASP1 antibody
 Reference Product  PubMed Publications
 ZYX antibody  >4 publications with LASP1 and ZYX
 LPP antibody  >2 publications with LASP1 and LPP
 TP53 antibody  >1 publications with LASP1 and TP53
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >18 publications with LASP1 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >7 publications with LASP1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with LASP1 and Carcinoma, Hepatocellular
 Cell Transformation, Neoplastic Antibodies  >5 publications with LASP1 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >5 publications with LASP1 and Liver Diseases
 Neoplasms, Experimental Antibodies  >5 publications with LASP1 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >2 publications with LASP1 and Disease Models, Animal
 Hyperplasia Antibodies  >2 publications with LASP1 and Hyperplasia
 Abnormalities, Drug-Induced Antibodies  >1 publications with LASP1 and Abnormalities, Drug-Induced
 Prenatal Injuries Antibodies  >1 publications with LASP1 and Prenatal Injuries
Organs/Tissues associated with anti-LASP1 antibody
 Organ/Tissue Name  Pubmed Publications
 Lymph Antibodies  >9 publications with LASP1 and Lymph
 Brain Antibodies  >9 publications with LASP1 and Brain
 Liver Antibodies  >8 publications with LASP1 and Liver
 Nerve Antibodies  >8 publications with LASP1 and Nerve
 Muscle Antibodies  >8 publications with LASP1 and Muscle
 Lymph Node Antibodies  >8 publications with LASP1 and Lymph Node
 Prostate Antibodies  >7 publications with LASP1 and Prostate
 Bone Antibodies  >5 publications with LASP1 and Bone
 Stomach Antibodies  >5 publications with LASP1 and Stomach
 Blood Antibodies  >4 publications with LASP1 and Blood
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