NP_671723.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,259 Da
NCBI Official Full Name
ceramide synthase 5 isoform 1
NCBI Official Synonym Full Names
ceramide synthase 5
NCBI Official Synonym Symbols
NCBI Protein Information
ceramide synthase 5; LAG1 homolog, ceramide synthase 5; LAG1 longevity assurance homolog 5
UniProt Protein Name
Ceramide synthase 5
UniProt Synonym Protein Names
LAG1 longevity assurance homolog 5
UniProt Synonym Gene Names
UniProt Entry Name
CERS5_HUMAN
NCBI Summary for LASS5
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for LASS5
LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.
Protein type: Transferase; DNA-binding; Membrane protein, integral; EC 2.3.1.24; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q13.12
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; endoplasmic reticulum; integral to membrane
Molecular Function: DNA binding; sphingosine N-acyltransferase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process
Research Articles on LASS5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-LASS5 antibody
Pathways associated with anti-LASS5 antibody
Diseases associated with anti-LASS5 antibody
Organs/Tissues associated with anti-LASS5 antibody
|