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anti-LCA5 antibody :: Rabbit anti-Human LCA5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7000773
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LCA5, Polyclonal Antibody

★Popular Item★
 Also Known As   

LCA5 Antibody

 Product Synonym Names    Lebercilin; Leber congenital amaurosis 5 protein; LCA5; C6orf152
 Product Gene Name   

anti-LCA5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604537
 3D Structure    ModBase 3D Structure for Q86VQ0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Lebercilin protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133728
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LCA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LCA5 antibody

   Might be involved in minus end-directed microtubule transport.
 Applications Tested/Suitable for anti-LCA5 antibody   

ELISA (EIA), Western Blot (WB)

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 Western Blot (WB) of anti-LCA5 antibody    Western blot
All lanes: LCA5 antibody at 18 ug/ml+Mouse kidney tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 81 kDa
Observed band size: 81 kDa

anti-LCA5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for LCA5. It may not necessarily be applicable to this product.
 NCBI GI #    170650672
 NCBI GeneID    167691
 NCBI Accession #    NP_001116241.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001122769.2 [Other Products]
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 UniProt Primary Accession #    Q86VQ0 [Other Products]
 UniProt Secondary Accession #    Q9BWX7; E1P542 [Other Products]
 UniProt Related Accession #    Q86VQ0 [Other Products]
 Molecular Weight    80,554 Da
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 NCBI Official Full Name    lebercilin
 NCBI Official Synonym Full Names    Leber congenital amaurosis 5
 NCBI Official Symbol    LCA5 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    lebercilin
 UniProt Protein Name    Lebercilin
 UniProt Synonym Protein Names   
Leber congenital amaurosis 5 protein
 Protein Family    Lebercilin
 UniProt Gene Name    LCA5 [Similar Products]
 UniProt Synonym Gene Names    C6orf152 [Similar Products]
 UniProt Entry Name    LCA5_HUMAN
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 NCBI Summary for LCA5    This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternatively spliced transcript variants are described. [provided by RefSeq, Oct 2009]
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 UniProt Comments for LCA5    LCA5: Might be involved in minus end-directed microtubule transport. Defects in LCA5 are the cause of Leber congenital amaurosis type 5 (LCA5). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. Belongs to the LCA5 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: axoneme; cilium

Molecular Function: protein binding; protein complex binding

Biological Process: intraflagellar transport; photoreceptor cell maintenance

Disease: Leber Congenital Amaurosis 5
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 Research Articles on LCA5    1. Identification of novel LCA5 mutations in patients with Leber congenital amaurosis and retinitis pigmentosa.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LCA5 antibodyDiseases associated with anti-LCA5 antibody
 Reference Product  PubMed Publications
 CRB1 antibody  >11 publications with LCA5 and CRB1
 GUCY2D antibody  >10 publications with LCA5 and GUCY2D
 RPE65 antibody  >10 publications with LCA5 and RPE65
 TULP1 antibody  >9 publications with LCA5 and TULP1
 AIPL1 antibody  >9 publications with LCA5 and AIPL1
 RDH12 antibody  >7 publications with LCA5 and RDH12
 Disease Name  Pubmed Publications
 Blindness Antibodies  >15 publications with LCA5 and Blindness
 Atrophy Antibodies  >7 publications with LCA5 and Atrophy
 Congenital Abnormalities Antibodies  >3 publications with LCA5 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >1 publications with LCA5 and Cardiovascular Diseases
 Abnormalities, Multiple Antibodies  >1 publications with LCA5 and Abnormalities, Multiple
 Nerve Degeneration Antibodies  >1 publications with LCA5 and Nerve Degeneration
 Reflex, Abnormal Antibodies  >1 publications with LCA5 and Reflex, Abnormal
Organs/Tissues associated with anti-LCA5 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >25 publications with LCA5 and Eye
 Brain Antibodies  >3 publications with LCA5 and Brain
 Trachea Antibodies  >1 publications with LCA5 and Trachea
 Testis Antibodies  >1 publications with LCA5 and Testis
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