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anti-LDB3 antibody :: Rabbit anti-Human LDB3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7043939
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LDB3, Polyclonal Antibody

★Popular Item★
 Also Known As   

LDB3 Antibody

 Product Synonym Names    LIM domain-binding protein 3; Protein cypher; Z-band alternatively spliced PDZ-motif protein; LDB3
 Product Gene Name   

anti-LDB3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601493
 3D Structure    ModBase 3D Structure for O75112
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human LIM domain-binding protein 3 protein (1-283AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82848 / sc-98653
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LDB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LDB3 antibody

   May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
 Applications Tested/Suitable for anti-LDB3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-LDB3 antibody    Western blot
All lanes: LDB3 antibody at 3.21ug/ml
Lane 1: Raji whole cell lysate
Lane 2: MCF7 whole cell lysate
Lane 3: A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 78,67,51,43,36,31,79 kDa
Observed band size: 77 kDa

anti-LDB3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-LDB3 antibody    Immunohistochemistry of paraffin-embedded human skeletal muscle tissue MBS7043939 at dilution 1:100
anti-LDB3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for LDB3. It may not necessarily be applicable to this product.
 NCBI GI #    122056614
 NCBI GeneID    11155
 NCBI Accession #    NP_001073583.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080114.1 [Other Products]
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 UniProt Primary Accession #    O75112 [Other Products]
 UniProt Secondary Accession #    Q5K6N9; Q5K6P0; Q5K6P1; Q96FH2; Q9Y4Z3; Q9Y4Z4; Q9Y4Z5; A2TDB7; A6NIV4; B4E3K3 [Other Products]
 UniProt Related Accession #    O75112 [Other Products]
 Molecular Weight    78,504 Da
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 NCBI Official Full Name    LIM domain-binding protein 3 isoform 2
 NCBI Official Synonym Full Names    LIM domain binding 3
 NCBI Official Symbol    LDB3 [Similar Products]
 NCBI Official Synonym Symbols   
MFM4; ZASP; CMD1C; CMH24; CMPD3; LVNC3; CYPHER; LDB3Z1; LDB3Z4; ORACLE; PDLIM6
[Similar Products]
 NCBI Protein Information    LIM domain-binding protein 3
 UniProt Protein Name    LIM domain-binding protein 3
 UniProt Synonym Protein Names   
Protein cypher; Z-band alternatively spliced PDZ-motif protein
 Protein Family    LIM domain-binding protein
 UniProt Gene Name    LDB3 [Similar Products]
 UniProt Entry Name    LDB3_HUMAN
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 NCBI Summary for LDB3    This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010]
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 UniProt Comments for LDB3    May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
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 Research Articles on LDB3    1. this is the first family with Arrhythmogenic right ventricular cardiomyopathy where a mutation in LDB3 is associated with Arrhythmogenic right ventricular cardiomyopathy
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-LDB3 antibodyOrgans/Tissues associated with anti-LDB3 antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >40 publications with LDB3 and Heart Diseases
 Cardiomegaly Antibodies  >20 publications with LDB3 and Cardiomegaly
 Hypertrophy Antibodies  >8 publications with LDB3 and Hypertrophy
 Disease Models, Animal Antibodies  >7 publications with LDB3 and Disease Models, Animal
 Abnormalities, Multiple Antibodies  >6 publications with LDB3 and Abnormalities, Multiple
 Atrophy Antibodies  >5 publications with LDB3 and Atrophy
 Fibrosis Antibodies  >4 publications with LDB3 and Fibrosis
 Necrosis Antibodies  >3 publications with LDB3 and Necrosis
 MYOPATHY, MYOFIBRILLAR, 4 Antibodies  >3 publications with LDB3 and MYOPATHY, MYOFIBRILLAR, 4
 Kidney Diseases Antibodies  >1 publications with LDB3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >66 publications with LDB3 and Muscle
 Heart Antibodies  >38 publications with LDB3 and Heart
 Nerve Antibodies  >4 publications with LDB3 and Nerve
 Brain Antibodies  >4 publications with LDB3 and Brain
 Embryonic Tissue Antibodies  >3 publications with LDB3 and Embryonic Tissue
 Eye Antibodies  >2 publications with LDB3 and Eye
 Kidney Antibodies  >2 publications with LDB3 and Kidney
 Lung Antibodies  >1 publications with LDB3 and Lung
 Vascular Antibodies  >1 publications with LDB3 and Vascular
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