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anti-LHB antibody :: Rabbit anti-Human, Mouse LHB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9409631
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LHB, Polyclonal Antibody

★Popular Item★
 Also Known As   

LHB antibody

 Product Synonym Names    CGB4; hLHB; LSH-B
 Product Gene Name   

anti-LHB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    152780
 3D Structure    ModBase 3D Structure for P01229
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    The antibody detects endogenous level of total LHB antibody.
 Purity/Purification    Antibodies were purified by affinity purification using immunogen.
 Form/Format    Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Peptide
 Immunogen Description    A synthetic peptide of human LHB.
 Target Name    LHB
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-LHB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LHB antibody

   This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
 Product Categories/Family for anti-LHB antibody    Total protein Ab
 Applications Tested/Suitable for anti-LHB antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-LHB antibody    Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200
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 Western Blot (WB) of anti-LHB antibody    Western blot analysis of extracts of K562 cell line, using LHB antibody.
anti-LHB antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-LHB antibody    Immunohistochemistry analysis of paraffin-embedded human liver cancer tissue using LHB antibody at dilution of 1:200 (x400 lens).
anti-LHB antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-LHB antibody    Immunohistochemistry analysis of paraffin-embedded human rectal cancer tissue using LHB antibody at dilution of 1:200 (x400 lens).
anti-LHB antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for LHB. It may not necessarily be applicable to this product.
 NCBI GI #    4504989
 NCBI GeneID    3972
 NCBI Accession #    NP_000885.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000894.2 [Other Products]
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 UniProt Primary Accession #    P01229 [Other Products]
 UniProt Secondary Accession #    Q9UDI0 [Other Products]
 UniProt Related Accession #    P01229 [Other Products]
 Molecular Weight    15kd
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 NCBI Official Full Name    lutropin subunit beta
 NCBI Official Synonym Full Names    luteinizing hormone beta polypeptide
 NCBI Official Symbol    LHB [Similar Products]
 NCBI Official Synonym Symbols   
CGB4; HH23; hLHB; LSH-B
[Similar Products]
 NCBI Protein Information    lutropin subunit beta
 UniProt Protein Name    Lutropin subunit beta
 UniProt Synonym Protein Names   
Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta
 Protein Family    Lutropin/choriogonadotropin
 UniProt Gene Name    LHB [Similar Products]
 UniProt Synonym Gene Names    Lutropin beta chain; LH-B; LSH-B; LSH-beta [Similar Products]
 UniProt Entry Name    LSHB_HUMAN
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 NCBI Summary for LHB    This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LHB    LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Hormone; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity; receptor binding

Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction

Disease: Fertile Eunuch Syndrome
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 Research Articles on LHB    1. the frequency of v-betaLH in Denmark is similar to a number of European countries
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LHB antibodyPathways associated with anti-LHB antibody
 Reference Product  PubMed Publications
 CGA antibody  >31 publications with LHB and CGA
 EGR1 antibody  >14 publications with LHB and EGR1
 LHCGR antibody  >11 publications with LHB and LHCGR
 CYP17A1 antibody  >7 publications with LHB and CYP17A1
 POMC antibody  >5 publications with LHB and POMC
 FOXO1 antibody  >2 publications with LHB and FOXO1
 Products by Pathway  Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-LHB antibodyOrgans/Tissues associated with anti-LHB antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >36 publications with LHB and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >36 publications with LHB and Cardiovascular Diseases
 Heart Diseases Antibodies  >22 publications with LHB and Heart Diseases
 Depressive Disorder Antibodies  >9 publications with LHB and Depressive Disorder
 Myocardial Infarction Antibodies  >8 publications with LHB and Myocardial Infarction
 Hyperplasia Antibodies  >7 publications with LHB and Hyperplasia
 Inflammation Antibodies  >7 publications with LHB and Inflammation
 Hypogonadism Antibodies  >6 publications with LHB and Hypogonadism
 Infertility, Female Antibodies  >6 publications with LHB and Infertility, Female
 Liver Diseases Antibodies  >6 publications with LHB and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >236 publications with LHB and Brain
 Pituitary Gland Antibodies  >74 publications with LHB and Pituitary Gland
 Placenta Antibodies  >7 publications with LHB and Placenta
 Embryonic Tissue Antibodies  >5 publications with LHB and Embryonic Tissue
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