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anti-LIPH antibody :: Rabbit LIPH Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7601028 anti-LIPH antibody
Unit / Price
0.1 mg  /  $265 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LIPH, Polyclonal Antibody

 Also Known As   

LIPH Rabbit Polyclonal

 Product Gene Name   

anti-LIPH antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604379
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >=95% as determined by SDS-PAGE
Immunogen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Lipase, member H
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 Preparation and Storage    PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LIPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-LIPH antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for LIPH. It may not necessarily be applicable to this product.
 NCBI GI #    823672616
 NCBI GeneID    200879
 NCBI Accession #    AKI71519.1 [Other Products]
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 UniProt Secondary Accession #    Q8TEC7; A2IBA7 [Other Products]
 UniProt Related Accession #    Q8WWY8 [Other Products]
 Molecular Weight    50,859 Da
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 NCBI Official Full Name    LIPH, partial
 NCBI Official Synonym Full Names    lipase H
 NCBI Official Symbol    LIPH [Similar Products]
 NCBI Official Synonym Symbols   
AH; LAH2; ARWH2; HYPT7; LPDLR; PLA1B; mPA-PLA1
[Similar Products]
 NCBI Protein Information    lipase member H
 UniProt Protein Name    Lipase member H
 UniProt Synonym Protein Names   
LPD lipase-related protein; Membrane-associated phosphatidic acid-selective phospholipase A1-alpha; mPA-PLA1 alpha; Phospholipase A1 member B
 Protein Family    Lipase
 UniProt Gene Name    LIPH [Similar Products]
 UniProt Synonym Gene Names    LPDLR; MPAPLA1; PLA1B; LIPH; mPA-PLA1 alpha [Similar Products]
 UniProt Entry Name    LIPH_HUMAN
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 NCBI Summary for LIPH    This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LIPH    LIPH: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). Defects in LIPH are the cause of hypotrichosis type 7 (HYPT7); also known as alopecia universalis congenita Mari type. A condition characterized by the presence of less than the normal amount of hair. Affected individuals have sparse or absent scalp, axillary and body hair and sparse eyebrows and eyelashes. Defects in LIPH are the cause of woolly hair autosomal recessive type 2 (ARWH2). A hair shaft disorder characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, woolly hair grows slowly and stops growing after a few inches. Under light microscopy, woolly hair shows some structural anomalies, including trichorrhexis nodosa and tapered ends. Some individuals may present with hypotrichosis. Belongs to the AB hydrolase superfamily. Lipase family.

Protein type: EC 3.1.1.-; Secreted, signal peptide; Secreted; Phospholipase

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: extracellular space; plasma membrane

Molecular Function: heparin binding; phospholipase activity

Biological Process: lipid catabolic process; lipid digestion

Disease: Hypotrichosis 7
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 Research Articles on LIPH    1. c.460_461AG>GA (p.Ser154Asp) in exon 3 and c.742C>A (p.His248Asn) in exon 6 associated with autosomal recessive woolly hair
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-LIPH antibodyDiseases associated with anti-LIPH antibody
 Products by Pathway  Pathway Diagram
 Digestion Of Dietary Lipid Pathway antibodies  Digestion Of Dietary Lipid Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Disease Name  Pubmed Publications
 Hypotrichosis Antibodies  >44 publications with LIPH and Hypotrichosis
 Cardiovascular Diseases Antibodies  >13 publications with LIPH and Cardiovascular Diseases
 Dyslipidemias Antibodies  >9 publications with LIPH and Dyslipidemias
 Heart Diseases Antibodies  >7 publications with LIPH and Heart Diseases
 Atherosclerosis Antibodies  >7 publications with LIPH and Atherosclerosis
 Lung Diseases Antibodies  >6 publications with LIPH and Lung Diseases
 Woolly hair, congenital Antibodies  >6 publications with LIPH and Woolly hair, congenital
 Fibrosis Antibodies  >4 publications with LIPH and Fibrosis
 Hypertension Antibodies  >4 publications with LIPH and Hypertension
 Lung Neoplasms Antibodies  >3 publications with LIPH and Lung Neoplasms
Organs/Tissues associated with anti-LIPH antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >17 publications with LIPH and Skin
 Lung Antibodies  >7 publications with LIPH and Lung
 Testis Antibodies  >2 publications with LIPH and Testis
 Pancreas Antibodies  >1 publications with LIPH and Pancreas
 Intestine Antibodies  >1 publications with LIPH and Intestine
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