NP_005349.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
LIM domain only protein 7 isoform 1
NCBI Official Synonym Full Names
LIM domain 7
NCBI Protein Information
LIM domain only protein 7
UniProt Protein Name
LIM domain only protein 7
UniProt Synonym Protein Names
F-box only protein 20; LOMP
UniProt Synonym Gene Names
UniProt Entry Name
LMO7_HUMAN
NCBI Summary for LMO7
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
UniProt Comments for LMO7
LMO7: contains a calponin homology (CH) domain, a PDZ domain, and a LIM domain; an F-box (FBX) domain is present in alternative splice variants. This protein is known to be upregulated in seven types of cancer. Translocates from the cell surface to the cytoplasm to the nucleus, regulates transcription of many genes, and may transmit mechanical signals from focal adhesions. Members of the LIM protein family carry the LIM domain, a unique cysteine-rich zinc-binding domain. Members of the FBX protein family are involved in protein-protein interactions. Four alternatively spliced isoforms have been described.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 13q22.2
Cellular Component: focal adhesion; cytoplasm; nucleus; ubiquitin ligase complex
Molecular Function: zinc ion binding; ubiquitin-protein ligase activity
Biological Process: regulation of cell adhesion; protein ubiquitination
Research Articles on LMO7
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Products associated with anti-LMO7 antibody
Pathways associated with anti-LMO7 antibody
Diseases associated with anti-LMO7 antibody
Organs/Tissues associated with anti-LMO7 antibody
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