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anti-LPAR4 antibody :: Rabbit LPAR4 / GPR23 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241437
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LPAR4 / GPR23, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Polyclonal to Human LPAR4 / GPR23

 Product Synonym Names    Anti-LPAR4 / GPR23 Antibody (C-Terminus) IHC-plus; LPAR4; G-protein coupled receptor 23; LPA-4; p2RY9; p2Y5-LIKE; p2Y purinoceptor 9; p2Y5-like receptor; p2Y9; G protein-coupled receptor 23; GPR23; LPA receptor 4; LPA4; Purinergic receptor 9; Human LPAR4; GPR23
 Product Gene Name   

anti-LPAR4 antibody

[Similar Products]
 Product Synonym Gene Name    GPR23 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300086
 3D Structure    ModBase 3D Structure for Q99677
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Gorilla, Human
Predicted Reactivity: Gibbon, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity)
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 Specificity    Human LPAR4 / GPR23. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 17 amino acid peptide from C-terminal cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Mouse, Rat, Bat, Hamster, Rabbit, Pig (94%).
 Immunogen Type    Synthetic peptide
 Immunogen    LPAR4 / GPR23 antibody was raised against synthetic 17 amino acid peptide from C-terminal cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Mouse, Rat, Bat, Hamster, Rabbit, Pig (94%); Monkey, Bovine, Panda, Horse (88%); Dog, Elephant (82%).
 Antigen Modification    C-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-LPAR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LPAR4 antibody

   GPR23 has been identified as a Lysophospholipid/Lysosphingolipid Receptor.
 Product Categories/Family for anti-LPAR4 antibody    Family: GPCR
Subfamily: Lysophospholipid/Lysosphingolipid
 Applications Tested/Suitable for anti-LPAR4 antibody   

Immunohistochemistry (IHC - Paraffin)

 Application Notes for anti-LPAR4 antibody    IHC-P (5 - 10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-LPAR4 antibody    Anti-LPAR4 / GPR23 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-LPAR4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for LPAR4. It may not necessarily be applicable to this product.
 NCBI GI #    4885311
 NCBI GeneID    2846
 NCBI Accession #    NP_005287.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005296.2 [Other Products]
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 UniProt Primary Accession #    Q99677 [Other Products]
 UniProt Secondary Accession #    O15132; Q502U9; Q6NSP5; B2RAC7 [Other Products]
 UniProt Related Accession #    Q99677 [Other Products]
 Molecular Weight    41,895 Da
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 NCBI Official Full Name    lysophosphatidic acid receptor 4
 NCBI Official Synonym Full Names    lysophosphatidic acid receptor 4
 NCBI Official Symbol    LPAR4 [Similar Products]
 NCBI Official Synonym Symbols   
LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE
[Similar Products]
 NCBI Protein Information    lysophosphatidic acid receptor 4; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23
 UniProt Protein Name    Lysophosphatidic acid receptor 4
 UniProt Synonym Protein Names   
G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9
 Protein Family    Lysophosphatidic acid receptor
 UniProt Gene Name    LPAR4 [Similar Products]
 UniProt Synonym Gene Names    GPR23; LPA4; P2RY9; LPA receptor 4; LPA-4; P2Y9 [Similar Products]
 UniProt Entry Name    LPAR4_HUMAN
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 NCBI Summary for LPAR4    This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]
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 UniProt Comments for LPAR4    LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: Xq21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway
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 Research Articles on LPAR4    1. Our data suggest that LPA4 signaling potentially modulates malignant behavior of SQ-20B cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LPAR4 antibodyPathways associated with anti-LPAR4 antibody
 Reference Product  PubMed Publications
 LPAR1 antibody  >4 publications with LPAR4 and LPAR1
 LPAR2 antibody  >3 publications with LPAR4 and LPAR2
 LPAR3 antibody  >2 publications with LPAR4 and LPAR3
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 LPA Receptor Mediated Events Pathway antibodies  LPA Receptor Mediated Events Pathway Diagram
 LPA4-mediated Signaling Events Pathway antibodies  LPA4-mediated Signaling Events Pathway Diagram
Diseases associated with anti-LPAR4 antibodyOrgans/Tissues associated with anti-LPAR4 antibody
 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >1 publications with LPAR4 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with LPAR4 and Neoplasm Metastasis
 Liver Diseases Antibodies  >1 publications with LPAR4 and Liver Diseases
 Skin Neoplasms Antibodies  >1 publications with LPAR4 and Skin Neoplasms
 Disease Models, Animal Antibodies  >1 publications with LPAR4 and Disease Models, Animal
 Liver Neoplasms, Experimental Antibodies  >1 publications with LPAR4 and Liver Neoplasms, Experimental
 Inflammation Antibodies  >1 publications with LPAR4 and Inflammation
 Neoplasms, Experimental Antibodies  >1 publications with LPAR4 and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with LPAR4 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with LPAR4 and Embryonic Tissue
 Thymus Antibodies  >1 publications with LPAR4 and Thymus
 Eye Antibodies  >1 publications with LPAR4 and Eye
 Brain Antibodies  >1 publications with LPAR4 and Brain
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