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anti-LRFN4 antibody :: Rabbit LRFN4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150801
Unit / Price
0.02 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LRFN4, Polyclonal Antibody

 Also Known As   

LRFN4 Antibody

 Product Synonym Names    LRFN4; SALM3; SALM3.; FIGLER6; SALM3; Leucine-rich repeat and fibronectin type-III domain-containing protein 4; leucine rich repeat and fibronectin type III domain containing 4
 Product Gene Name   

anti-LRFN4 antibody

[Similar Products]
 Antibody/Peptide Pairs    LRFN4 peptide (MBS151843) is used for blocking the activity of LRFN4 antibody (MBS150801)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612810
 3D Structure    ModBase 3D Structure for Q6PJG9
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    This antibody is predicted to not cross-react with other members of the LRFN family.
 Purity/Purification    LRFN4 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    LRFN4 antibody was raised against a 14amino acid synthetic peptide near the carboxy terminus of human LRFN4.
 Buffer    LRFN4 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    LRFN4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-LRFN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-LRFN4 antibody

   LRFN4 Antibody: LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
 Applications Tested/Suitable for anti-LRFN4 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-LRFN4 antibody    LRFN4 antibody can be used for detection of LRFN4 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
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 Western Blot (WB) of anti-LRFN4 antibody    Western blot analysis of LRFN4 in rat brain lysate with LRFN4 antibody at 1 μg/mL.
anti-LRFN4 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-LRFN4 antibody    Immunohistochemistry of LRFN4 in mouse brain tissue with LRFN4 antibody at 2.5 μg/mL.
anti-LRFN4 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-LRFN4 antibody    Immunofluorescence of LRFN4 in mouse brain tissue with LRFN4 antibody at 20 μg/mL.
anti-LRFN4 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for LRFN4. It may not necessarily be applicable to this product.
 NCBI GI #    62286924
 NCBI GeneID    78999
 NCBI Accession #    Q6PJG9.1 [Other Products]
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 UniProt Primary Accession #    Q6PJG9 [Other Products]
 UniProt Secondary Accession #    Q4VBZ3; Q59GV4; Q8N644; Q9BWJ0 [Other Products]
 UniProt Related Accession #    Q6PJG9 [Other Products]
 Molecular Weight    66,860 Da
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 NCBI Official Full Name    Leucine-rich repeat and fibronectin type-III domain-containing protein 4
 NCBI Official Synonym Full Names    leucine rich repeat and fibronectin type III domain containing 4
 NCBI Official Symbol    LRFN4 [Similar Products]
 NCBI Official Synonym Symbols   
SALM3; SALM3.; FIGLER6
[Similar Products]
 NCBI Protein Information    leucine-rich repeat and fibronectin type-III domain-containing protein 4; fibronectin type III, immunoglobulin and leucine rich repeat domains 6
 UniProt Protein Name    Leucine-rich repeat and fibronectin type-III domain-containing protein 4
 Protein Family    Leucine-rich repeat and fibronectin type-III domain-containing protein
 UniProt Gene Name    LRFN4 [Similar Products]
 UniProt Synonym Gene Names    SALM3 [Similar Products]
 UniProt Entry Name    LRFN4_HUMAN
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 UniProt Comments for LRFN4    LRFN4: Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery. Belongs to the LRFN family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: integral to membrane
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 Research Articles on LRFN4    1. LRFN4 complexed with 14-3-3s and NCK1 to mediate elongation in monocytic cells via Rac-1-mediated actin cytoskeleton reorganization
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LRFN4 antibodyDiseases associated with anti-LRFN4 antibody
 Reference Product  PubMed Publications
 DLG4 antibody  >2 publications with LRFN4 and DLG4
 NCK1 antibody  >1 publications with LRFN4 and NCK1
 Disease Name  Pubmed Publications
 Autistic Disorder Antibodies  >1 publications with LRFN4 and Autistic Disorder
Organs/Tissues associated with anti-LRFN4 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with LRFN4 and Blood
 Brain Antibodies  >1 publications with LRFN4 and Brain
 Embryonic Tissue Antibodies  >1 publications with LRFN4 and Embryonic Tissue
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