Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow LTB4R rightarrow Polyclonal LTB4R  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • FKBP-type peptidyl-prolyl cis-trans isomerase FkpA  Recombinant Protein
 • C Reactive Protein (CRP) Antibody
 • Myoglobin (Antigen grade) (MB) Protein
 • USP33 - VDU1 Antibody
 • TLR5 Antibody
 • Annexin A1 (ANXA1) ELISA Kit
 • CX3CL1-Fractalkine Recombinant Protein
 • RNA Binding Motif Protein 20 (RBM20) ELISA Kit
 • Gelsolin ELISA Kit
 • Fetuin A (FETU A) ELISA Kit
 • Heparan Sulfate Proteoglycan (HSPG) Antibody
 • PGF2-alpha Antibody
 • Glucose-6-phosphate isomerase (GPI) Recombinant Protein
 • Soluble CD44V9 (SCD44V9) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-LTB4R antibody :: Rabbit Leukotriene B4 Receptor / BLT1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS243711
Unit / Price
0.1 mL  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leukotriene B4 Receptor / BLT1 (LTB4R), Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal (IgG) to Human Leukotriene B4 Receptor / BLT1

 Product Synonym Names    Anti-Leukotriene B4 Receptor / BLT1 Antibody IHC-plus; BLT; BLTR; Blt-1; Chemokine receptor-like 1; G protein-coupled receptor 16; GPR16; Leukotriene B4 receptor; Leukotriene B4 receptor 1; G-protein coupled receptor 16; LTBR1; p2Y purinoceptor 7; p2Y7; LTB4-R 1; p2RY7; CMKRL1; LTB4-R1; LTB4R1; Human Leukotriene B4 Receptor; BLT1
 Product Gene Name   

anti-LTB4R antibody

[Similar Products]
 Product Synonym Gene Name    BLT1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    601531
 3D Structure    ModBase 3D Structure for Q15722
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
Section Bar
 Purity/Purification    Affinity Purified
 Form/Format    TBS pH 7.4, containing 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide
 Concentration    1 mg/ml (lot specific)
Section Bar
 Target Species    Human
 Non Reactive Species    Mouse
 Immunogen Description    Human BLT1 receptor amino acids 331-352 (ALEPGPSESLTASSPLKLNELN).
 Immunogen    Leukotriene B4 Receptor / BLT1 antibody was raised against human BLT1 receptor amino acids 331-352 (ALEPGPSESLTASSPLKLNELN).
Section Bar
 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
 Other Notes    Small volumes of anti-LTB4R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-LTB4R antibody

   BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor (Yokomizo et al., 1997).
 Product Categories/Family for anti-LTB4R antibody    Family: GPCR
Subfamily: Chemoattractant
 Applications Tested/Suitable for anti-LTB4R antibody   

Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB)

 Application Notes for anti-LTB4R antibody    ICC, IHC-P (5 ug/ml), WB (1:200)
Section Bar
 Immunohistochemistry (IHC) of anti-LTB4R antibody    Anti-Leukotriene B4 Receptor antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-LTB4R antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-LTB4R antibody    Anti-Leukotriene B4 Receptor antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-LTB4R antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Western Blot (WB) of anti-LTB4R antibody    Western blot of Leukotriene B4 Receptor / BLT1 antibody.
anti-LTB4R antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for LTB4R. It may not necessarily be applicable to this product.
 NCBI GI #    221218998
 NCBI GeneID    1241
 NCBI Accession #    NP_001137391.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001143919.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q15722 [Other Products]
 UniProt Secondary Accession #    Q13305; Q53XV5; Q92641; Q9BSU5 [Other Products]
 UniProt Related Accession #    Q15722 [Other Products]
 Molecular Weight    37,557 Da
Table BarTOPTable Bar
 NCBI Official Full Name    leukotriene B4 receptor 1
 NCBI Official Synonym Full Names    leukotriene B4 receptor
 NCBI Official Symbol    LTB4R [Similar Products]
 NCBI Official Synonym Symbols   
BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1
[Similar Products]
 NCBI Protein Information    leukotriene B4 receptor 1; LTB4-R1; LTB4-R 1; P2Y purinoceptor 7; chemokine receptor-like 1; G protein-coupled receptor 16; G-protein coupled receptor 16; chemoattractant receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7
 UniProt Protein Name    Leukotriene B4 receptor 1
 UniProt Synonym Protein Names   
Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7
 Protein Family    Leukotriene B4 receptor
 UniProt Gene Name    LTB4R [Similar Products]
 UniProt Synonym Gene Names    BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; LTB4-R 1; LTB4-R1; P2Y7 [Similar Products]
 UniProt Entry Name    LT4R1_HUMAN
Section Bar
 UniProt Comments for LTB4R    LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: leukotriene B4 receptor activity; nucleotide binding; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; muscle contraction; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cell motility; inflammatory response
Table BarTOPTable Bar
 Research Articles on LTB4R    1. we show that orchestrated action of CXCR2 and leukotriene B4 receptor BLT1 plays a key role in neutrophil recruitment during the development of imiquimod (IMQ)-induced psoriatic skin lesions in mice
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-LTB4R antibodyPathways associated with anti-LTB4R antibody
 Reference Product  PubMed Publications
 CYSLTR2 antibody  >1 publications with LTB4R and CYSLTR2
 ADRBK1 antibody  >1 publications with LTB4R and ADRBK1
 CCK antibody  >1 publications with LTB4R and CCK
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Leukotriene Receptors Pathway antibodies  Leukotriene Receptors Pathway Diagram
Diseases associated with anti-LTB4R antibodyOrgans/Tissues associated with anti-LTB4R antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >34 publications with LTB4R and Inflammation
 Asthma Antibodies  >16 publications with LTB4R and Asthma
 Necrosis Antibodies  >8 publications with LTB4R and Necrosis
 Pancreatic Neoplasms Antibodies  >2 publications with LTB4R and Pancreatic Neoplasms
 Leukemia, Myeloid Antibodies  >2 publications with LTB4R and Leukemia, Myeloid
 Fibrosis Antibodies  >2 publications with LTB4R and Fibrosis
 Disease Models, Animal Antibodies  >2 publications with LTB4R and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >2 publications with LTB4R and Neoplasms, Experimental
 Leukemia Antibodies  >2 publications with LTB4R and Leukemia
 Bronchial Hyperreactivity Antibodies  >1 publications with LTB4R and Bronchial Hyperreactivity
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >47 publications with LTB4R and Blood
 Lung Antibodies  >14 publications with LTB4R and Lung
 Skin Antibodies  >5 publications with LTB4R and Skin
 Bone Marrow Antibodies  >5 publications with LTB4R and Bone Marrow
 Kidney Antibodies  >3 publications with LTB4R and Kidney
 Spleen Antibodies  >2 publications with LTB4R and Spleen
 Uterus Antibodies  >2 publications with LTB4R and Uterus
 Eye Antibodies  >1 publications with LTB4R and Eye
 Ovary Antibodies  >1 publications with LTB4R and Ovary
 Brain Antibodies  >1 publications with LTB4R and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions