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anti-LEAP2 antibody :: Rabbit anti-Human Liver Expressed Antimicrobial Peptide 2 (LEAP2) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2015535 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Western Blot
Unit / Price
0.01 mg  /  $125 +1 FREE 8GB USB
0.02 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $200 +1 FREE 8GB USB
0.1 mg  /  $260 +1 FREE 8GB USB
0.2 mg  /  $400 +1 FREE 8GB USB
1 mg  /  $955 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Liver Expressed Antimicrobial Peptide 2 (LEAP2), Polyclonal Antibody

★Popular Item★
 Also Known As   

FITC-linked Antibody to Liver Expressed Antimicrobial Peptide 2 (LEAP2)

 Product Gene Name   

anti-LEAP2 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Liver Expressed Antimicrobial Peptide 2 (LEAP2) (MBS2001931)
FITC Conjugated Antibody: Liver Expressed Antimicrobial Peptide 2 (LEAP2) (MBS2015535)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_000005.9 (132209358..132210582). Location: 5q31.1
 OMIM    611373
 3D Structure    ModBase 3D Structure for Q969E1
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against LEAP2. It has been selected for its ability to recognize LEAP2 in immunohistochemical staining and western blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    100ug/mL (lot specific)
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 UOM    100ug
 Immunogen    Recombinant LEAP2 (Ser23~Gln76) with two N-terminal Tags, His-tag and GST-tag expressed in E.coli.
  Accession No.    RPH750Hu01
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2001931
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-LEAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-LEAP2 antibody    FITC Antibody
 Applications Tested/Suitable for anti-LEAP2 antibody   

Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)

 Application Notes for anti-LEAP2 antibody    Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
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 Western Blot of anti-LEAP2 antibody    anti-LEAP2 antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for LEAP2. It may not necessarily be applicable to this product.
 NCBI GI #    16418465
 NCBI GeneID    116842
 NCBI Accession #    NP_443203.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_052971.2 [Other Products]
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 UniProt Primary Accession #    Q969E1 [Other Products]
 UniProt Secondary Accession #    D3DQ91 [Other Products]
 UniProt Related Accession #    Q969E1 [Other Products]
 Molecular Weight    39kDa
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 NCBI Official Full Name    liver-expressed antimicrobial peptide 2
 NCBI Official Synonym Full Names    liver expressed antimicrobial peptide 2
 NCBI Official Symbol    LEAP2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    liver-expressed antimicrobial peptide 2
 UniProt Protein Name    Liver-expressed antimicrobial peptide 2
 Protein Family    Liver-expressed antimicrobial peptide
 UniProt Gene Name    LEAP2 [Similar Products]
 UniProt Synonym Gene Names    LEAP-2 [Similar Products]
 UniProt Entry Name    LEAP2_HUMAN
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 NCBI Summary for LEAP2    This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014]
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 UniProt Comments for LEAP2    LEAP2: Has an antimicrobial activity. Belongs to the LEAP2 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular region

Biological Process: defense response to bacterium
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 Research Articles on LEAP2    1. This study reveals that LEAP-2 has a novel fold for a cationic antimicrobial peptide and suggests that although LEAP-2 exhibits antimicrobial activity under low-salt conditions, there is likely to be another physiological role for the peptide.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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