NP_005759.4
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
lysophospholipid acyltransferase 5
NCBI Official Synonym Full Names
lysophosphatidylcholine acyltransferase 3
NCBI Official Synonym Symbols
C3F; LPCAT; LPSAT; OACT5; nessy; MBOAT5; LPLAT 5 [Similar Products]
NCBI Protein Information
lysophospholipid acyltransferase 5
UniProt Protein Name
Lysophospholipid acyltransferase 5
UniProt Synonym Protein Names
1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); Lysophosphatidylcholine acyltransferase; LPCAT; Lyso-PC acyltransferase; Lysophosphatidylcholine acyltransferase 3; Lyso-PC acyltransferase 3; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 5; O-acyltransferase domain-containing protein 5
UniProt Synonym Gene Names
MBOAT5; OACT5; LPLAT 5; LPCAT; Lyso-PC acyltransferase; Lyso-PC acyltransferase 3; LPSAT; Lyso-PS acyltransferase; O-acyltransferase domain-containing protein 5 [Similar Products]
UniProt Comments for LPCAT3
MBOAT5: Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Belongs to the membrane-bound acyltransferase family.
Protein type: EC 2.3.1.23; EC 2.3.1.n6; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: endoplasmic reticulum membrane; integral component of membrane; membrane
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity
Biological Process: phospholipid biosynthetic process
Research Articles on LPCAT3
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Products associated with anti-LPCAT3 antibody
Pathways associated with anti-LPCAT3 antibody
Diseases associated with anti-LPCAT3 antibody
Organs/Tissues associated with anti-LPCAT3 antibody
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