NP_032842.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
platelet endothelial cell adhesion molecule isoform 2
NCBI Official Synonym Full Names
platelet/endothelial cell adhesion molecule 1
NCBI Protein Information
platelet endothelial cell adhesion molecule
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Synonym Protein Names
CD_antigen: CD31
UniProt Synonym Gene Names
UniProt Entry Name
PECA1_MOUSE
UniProt Comments for Pecam1
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Protein type: Membrane protein, integral; Cell adhesion
Cellular Component: extracellular space; cell surface; smooth muscle contractile fiber; membrane; integral to membrane; plasma membrane; intracellular; cell junction; external side of plasma membrane; lipid raft
Molecular Function: protein binding
Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; wound healing; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of actin filament polymerization; diapedesis; positive regulation of leukocyte migration; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction
Product References and Citations for anti-Pecam1 antibody
DeLisser, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18616-18621(2010) Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010) Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010) Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010) Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010)
Research Articles on Pecam1
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Products associated with anti-Pecam1 antibody
Diseases associated with anti-Pecam1 antibody
Organs/Tissues associated with anti-Pecam1 antibody
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