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anti-M-CK antibody :: Rabbit anti-Human M-CK Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9401572
Unit / Price
0.05 mL  /  $200 +1 FREE 8GB USB
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

M-CK, Polyclonal Antibody

 Also Known As   

M-CK Antibody

 Product Synonym Names    CKM; CKMM.; EC 2.7.3.2; KCRM; creatine kinase
 Product Gene Name   

anti-M-CK antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123310
 3D Structure    ModBase 3D Structure for P06732
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody detects endogenous levels of total M-CK protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Peptide
 Immunogen Description    Synthesized peptide derived from N-terminal of human M-CK.
 Target Name    M-CK
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-M-CK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-M-CK antibody

   Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.Grimwood J., Nature 428:529-535(2004).Hamburg R.J., J. Biol. Chem. 265:6403-6409(1990).Tang L., Acta Crystallogr. D 55:669-670(1999).
 Product Categories/Family for anti-M-CK antibody    Total protein Ab
 Applications Tested/Suitable for anti-M-CK antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-M-CK antibody    Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
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 Western Blot (WB) of anti-M-CK antibody    Western blot analysis of extracts from HUVEC cells, HepG2 cells, Jurkat cells and HeLa cells, using M-CK antibody.
anti-M-CK antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-M-CK antibody    Immunohistochemistry analysis of paraffin-embedded human heart tissue using M-CK antibody.
anti-M-CK antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-M-CK antibody    Immunofluorescence analysis of HepG2 cells, using M-CK antibody.
anti-M-CK antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for M-CK. It may not necessarily be applicable to this product.
 NCBI GI #    21536288
 NCBI GeneID    1158
 NCBI Accession #    NP_001815.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001824.4 [Other Products]
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 UniProt Primary Accession #    P06732 [Other Products]
 UniProt Secondary Accession #    Q96QL9 [Other Products]
 UniProt Related Accession #    P06732 [Other Products]
 Molecular Weight    43,101 Da
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 NCBI Official Full Name    creatine kinase M-type
 NCBI Official Synonym Full Names    creatine kinase, muscle
 NCBI Official Symbol    CKM [Similar Products]
 NCBI Official Synonym Symbols   
CKMM; M-CK
[Similar Products]
 NCBI Protein Information    creatine kinase M-type
 UniProt Protein Name    Creatine kinase M-type
 UniProt Synonym Protein Names   
Creatine kinase M chain; M-CK
 UniProt Gene Name    CKM [Similar Products]
 UniProt Synonym Gene Names    CKMM [Similar Products]
 UniProt Entry Name    KCRM_HUMAN
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 NCBI Summary for M-CK    The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
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 UniProt Comments for M-CK    CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Kinase, other; EC 2.7.3.2; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytosol

Molecular Function: creatine kinase activity; ATP binding

Biological Process: phosphocreatine biosynthetic process; phosphorylation; creatine metabolic process
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 Research Articles on M-CK    1. CK-MB levels were higher after ERCP in non-ischemic patients compared with a myocardial ischemia group. Creatine phosphokinase levels did not differ significantly between groups.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-M-CK antibodyPathways associated with anti-M-CK antibody
 Reference Product  PubMed Publications
 CKB antibody  >15 publications with M-CK and CKB
 GAMT antibody  >1 publications with M-CK and GAMT
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
 Urea Cycle And Metabolism Of Amino Groups Pathway antibodies  Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
Diseases associated with anti-M-CK antibodyOrgans/Tissues associated with anti-M-CK antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >13 publications with M-CK and Heart Diseases
 Kidney Diseases Antibodies  >7 publications with M-CK and Kidney Diseases
 Myocardial Infarction Antibodies  >7 publications with M-CK and Myocardial Infarction
 Disease Models, Animal Antibodies  >6 publications with M-CK and Disease Models, Animal
 Inflammation Antibodies  >4 publications with M-CK and Inflammation
 Liver Neoplasms Antibodies  >4 publications with M-CK and Liver Neoplasms
 Ischemia Antibodies  >4 publications with M-CK and Ischemia
 Weight Loss Antibodies  >3 publications with M-CK and Weight Loss
 Liver Diseases Antibodies  >3 publications with M-CK and Liver Diseases
 Cardiomyopathies Antibodies  >3 publications with M-CK and Cardiomyopathies
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >59 publications with M-CK and Muscle
 Heart Antibodies  >28 publications with M-CK and Heart
 Kidney Antibodies  >11 publications with M-CK and Kidney
 Brain Antibodies  >9 publications with M-CK and Brain
 Liver Antibodies  >7 publications with M-CK and Liver
 Lung Antibodies  >6 publications with M-CK and Lung
 Embryonic Tissue Antibodies  >4 publications with M-CK and Embryonic Tissue
 Bone Antibodies  >4 publications with M-CK and Bone
 Vascular Antibodies  >4 publications with M-CK and Vascular
 Nerve Antibodies  >2 publications with M-CK and Nerve
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