NP_003957.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
semaphorin-5A
NCBI Official Synonym Full Names
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
NCBI Official Synonym Symbols
NCBI Protein Information
semaphorin-5A
UniProt Protein Name
Semaphorin-5A
UniProt Synonym Protein Names
Semaphorin-F; Sema F
UniProt Synonym Gene Names
UniProt Entry Name
SEM5A_HUMAN
NCBI Summary for SEMA5A
This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010]
UniProt Comments for SEMA5A
SEMA5A: a single-pass type I membrane protein that may act as positive axonal guidance cues.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p15.2
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: syndecan binding; heparan sulfate proteoglycan binding; axon guidance receptor activity; semaphorin receptor binding
Biological Process: nervous system development; axon guidance; positive regulation of actin filament depolymerization; axonal fasciculation; negative regulation of cell adhesion; negative regulation of axon extension involved in axon guidance; diencephalon development; patterning of blood vessels; positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; blood vessel endothelial cell proliferation during sprouting angiogenesis; cell-cell signaling; positive chemotaxis; positive regulation of axon extension involved in axon guidance; positive regulation of endothelial cell proliferation; cell adhesion
Product References and Citations for anti-SEMA5A antibody
Bialecka,M., Neurosci. Lett. 399 (1-2), 121-123 (2006) Melin,M., Neuropsychobiology 54 (1), 64-69 (2006)
Research Articles on SEMA5A
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Products associated with anti-SEMA5A antibody
Pathways associated with anti-SEMA5A antibody
Diseases associated with anti-SEMA5A antibody
Organs/Tissues associated with anti-SEMA5A antibody
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