NP_004924.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
cadherin-15 preproprotein
NCBI Official Synonym Full Names
cadherin 15
NCBI Protein Information
cadherin-15
UniProt Protein Name
Cadherin-15
UniProt Synonym Protein Names
Cadherin-14; Muscle cadherin; M-cadherin
UniProt Synonym Gene Names
NCBI Summary for CDH15
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]
UniProt Comments for CDH15
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Product References and Citations for anti-CDH15 antibody
(1) Kang, J.S., Feinleib, J.L., Knox, S., et, al Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.Proc. Natl. Acad. Sci.2003; 100 (7):3989-3994.
Research Articles on CDH15
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Products associated with anti-CDH15 antibody
Pathways associated with anti-CDH15 antibody
Diseases associated with anti-CDH15 antibody
Organs/Tissues associated with anti-CDH15 antibody
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