NP_001013858.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 83 kDa Predicted: 84 kDa
NCBI Official Full Name
mitotic spindle assembly checkpoint protein MAD1 isoform a
NCBI Official Synonym Full Names
mitotic arrest deficient 1 like 1
NCBI Protein Information
mitotic spindle assembly checkpoint protein MAD1
UniProt Protein Name
Mitotic spindle assembly checkpoint protein MAD1
UniProt Synonym Protein Names
Mitotic arrest deficient 1-like protein 1; MAD1-like protein 1; Mitotic checkpoint MAD1 protein homolog; HsMAD1; hMAD1; Tax-binding protein 181
UniProt Synonym Gene Names
NCBI Summary for MAD1L1
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
UniProt Comments for MAD1L1
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Research Articles on MAD1L1
Precautions
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Disclaimer
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Products associated with anti-MAD1L1 antibody
Pathways associated with anti-MAD1L1 antibody
Diseases associated with anti-MAD1L1 antibody
Organs/Tissues associated with anti-MAD1L1 antibody
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