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Add To Compare List anti-MAOB antibody :: Rabbit MAOB Polyclonal Antibody Catalog # MBS9607120 Unit / Price 0.1 mL / $270 +1 FREE 8GB USB 0.2 mL / $315 +1 FREE 8GB USB 5x0.2 mL / $1,245 +1 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name MAOB, Polyclonal Antibody Popular Item Full Product Name MAOB Antibody Product Synonym Names Adrenalin oxidase; Amine oxidase (flavin containing); Amine oxidase [flavin-containing] B; AOFB_HUMAN; MAO, brain; MAO, platelet; MAO-B; MAOB; MGC26382; Monoamine oxidase B; Monoamine oxidase type B; OTTHUMP00000023166; Tyramine oxidase Product Gene Name anti-MAOB antibody[Similar Products] Antibody/Peptide Pairs MAOB peptide (MBS9625836) is used for blocking the activity of MAOB antibody (MBS9607120) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP 3D Structure ModBase 3D Structure for P27338 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Specificity MAOB antibody detects endogenous levels of total MAOB Purity/Purification The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin. Form/Format LiquidPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1mg/ml (lot specific) Immunogen A synthesized peptide derived from human MAOB Subcellular Location Mitochondrion Outer Membrane Predicted Cross Reactivity Pig, Bovine, Sheep, Rabbit, Dog Similarity Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%) Conjugation Unconjugated Preparation and Storage Store at -20 degree C. Stable for 12 months from date of receipt. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire. Other Notes Small volumes of anti-MAOB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-MAOB antibody Description: The MAOB gene encodes a 520-amino acid protein with a molecular mass of 58.8 kD and shows 70% amino acid identity to MAOA. MAOA and MAOB are present in the outer mitochondrial membrane in the central nervous system and peripheral tissues.A comparison of highly purified human placental MAOA and human liver MAOB revealed that the A form of the enzyme is larger by 2 kDa and only one potential N-glycosylation site exists in each protein, with each site in a different relevant position(PMID:3387449). This antibody is specific to MAOB.Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.Subunit Structure: Monomer, homo-or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity).Similarity: Belongs to the flavin monoamine oxidase family. Applications Tested/Suitable for anti-MAOB antibody Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) Application Notes for anti-MAOB antibody WB: 1:500-1:2000IHC: 1:50-1:200IF: 1:100-500Peptide ELISA: 1:20000-1:40000 Immunohistochemistry (IHC) of anti-MAOB antibody MBS9607120 at 1/100 staining Human gastric tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Immunofluorescene (IF) of anti-MAOB antibody MBS9607120 staining HeLa cells by ICC/IF. Cells were fixed with PFA and permeabilized in 0.1% saponin prior to blocking in 10% serum for 45 minutes at 37 degree C. The primary antibody was diluted 1/200 and incubated with the sample for 1 hour at 37 degree C. A Alexa Fluor 594 conjugated goat polyclonal to rabbit IgG (H+L), diluted 1/600 was used as secondary antibody. Western Blot (WB) of anti-MAOB antibody Western blot analysis of Mouse kidney lysate, using MAOB Antibody. The lane on the left is treated with the antigen-specific peptide. TOP NCBI/Uniprot data below describe general gene information for MAOB. It may not necessarily be applicable to this product. NCBI GI # 38202207 NCBI GeneID 4129 NCBI Accession # NP_000889.3 [Other Products] NCBI GenBank Nucleotide # NM_000898.4 [Other Products] UniProt Primary Accession # P27338 [Other Products] UniProt Secondary Accession # Q7Z6S2; B2R6R3; B7Z5H3; D3DWC3[Other Products] UniProt Related Accession # P27338[Other Products] Molecular Weight Observed: 59 kDaPredicted: 59 kDa TOP NCBI Official Full Name amine oxidase NCBI Official Synonym Full Names monoamine oxidase B NCBI Official Symbol MAOB [Similar Products] NCBI Protein Information amine oxidase [flavin-containing] B UniProt Protein Name Amine oxidase [flavin-containing] B UniProt Synonym Protein Names Monoamine oxidase type B; MAO-B Protein Family Amine oxidase UniProt Gene Name MAOB [Similar Products] UniProt Synonym Gene Names MAO-B [Similar Products] TOP NCBI Summary for MAOB The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] TOP UniProt Comments for MAOB Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Research Articles on MAOB 1. Our observations provide new information on the genotype-phenotype relations of MAOA/B and EFHC2 genes involved in the contiguous deletions of Norrie disease.Based on the case of our observation, contiguous deletion with only one of the MAO genes (MAOB) may not cause psychomotor disability, and deletion of EFHC2may not contribute to epilepsy. 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TOP Products associated with anti-MAOB antibody Reference Product PubMed Publications COMT antibody >30 publications with MAOB and COMT DBH antibody >5 publications with MAOB and DBH DDC antibody >5 publications with MAOB and DDC CYP2D6 antibody >4 publications with MAOB and CYP2D6 Pathways associated with anti-MAOB antibody Products by Pathway Pathway Diagram Alcoholism Pathway antibodies Alcoholism Pathway Diagram Alcoholism Pathway antibodies Alcoholism Pathway Diagram Alpha-synuclein Signaling Pathway antibodies Alpha-synuclein Signaling Pathway Diagram Amine Oxidase Reactions Pathway antibodies Amine Oxidase Reactions Pathway Diagram Amphetamine Addiction Pathway antibodies Amphetamine Addiction Pathway Diagram Amphetamine Addiction Pathway antibodies Amphetamine Addiction Pathway Diagram Arginine And Proline Metabolism Pathway antibodies Arginine And Proline Metabolism Pathway Diagram Arginine And Proline Metabolism Pathway antibodies Arginine And Proline Metabolism Pathway Diagram Biogenic Amines Are Oxidatively Deaminated To Aldehydes By MAOA And MAOB Pathway antibodies Biogenic Amines Are Oxidatively Deaminated To Aldehydes By MAOA And MAOB Pathway Diagram Biological Oxidations Pathway antibodies Biological Oxidations Pathway Diagram Diseases associated with anti-MAOB antibody Disease Name Pubmed Publications Mental Disorders Antibodies >68 publications with MAOB and Mental Disorders Movement Disorders Antibodies >46 publications with MAOB and Movement Disorders Parkinsonian Disorders Antibodies >42 publications with MAOB and Parkinsonian Disorders Parkinson Disease Antibodies >40 publications with MAOB and Parkinson Disease Schizophrenia Antibodies >15 publications with MAOB and Schizophrenia Autistic Disorder Antibodies >6 publications with MAOB and Autistic Disorder Depressive Disorder Antibodies >5 publications with MAOB and Depressive Disorder Bipolar Disorder Antibodies >5 publications with MAOB and Bipolar Disorder Learning Disorders Antibodies >4 publications with MAOB and Learning Disorders Cognition Disorders Antibodies >3 publications with MAOB and Cognition Disorders Organs/Tissues associated with anti-MAOB antibody Organ/Tissue Name Pubmed Publications Brain Antibodies >64 publications with MAOB and Brain Nerve Antibodies >14 publications with MAOB and Nerve Liver Antibodies >9 publications with MAOB and Liver Eye Antibodies >7 publications with MAOB and Eye Muscle Antibodies >6 publications with MAOB and Muscle Adrenal Gland Antibodies >5 publications with MAOB and Adrenal Gland Kidney Antibodies >4 publications with MAOB and Kidney Pituitary Gland Antibodies >2 publications with MAOB and Pituitary Gland Thyroid Antibodies >2 publications with MAOB and Thyroid Skin Antibodies >2 publications with MAOB and Skin TOP © 2006-24 MyBioSource.com. 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