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anti-MAPRE2 antibody :: Rabbit anti-Human, Mouse MAPRE2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7052809
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MAPRE2, Polyclonal Antibody

★Popular Item★
 Also Known As   

MAPRE2 Antibody

 Product Synonym Names    Microtubule-associated protein RP/EB family member 2; APC-binding protein EB2; End-binding protein 2; EB2; MAPRE2; RP1
 Product Gene Name   

anti-MAPRE2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    X94232 mRNA
 3D Structure    ModBase 3D Structure for Q15555
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Microtubule-associated protein RP/EB family member 2 protein (159-240AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MAPRE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MAPRE2 antibody

   May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
 Applications Tested/Suitable for anti-MAPRE2 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-MAPRE2 antibody    WB: 1:500-1:5000
IF: 1:50-1:200
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 Western Blot (WB) of anti-MAPRE2 antibody    Western Blot
Positive WB detected in: Mouse brain tissue
All lanes: MAPRE2 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38,30,36,33,31 KDa
Observed band size: 38,36 KDa

anti-MAPRE2 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-MAPRE2 antibody    Immunofluorescent analysis of HepG2 cells using MBS7052809 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-MAPRE2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for MAPRE2. It may not necessarily be applicable to this product.
 NCBI GI #    219842325
 NCBI GeneID    10982
 NCBI Accession #    NP_001137298.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001143826.2 [Other Products]
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 UniProt Primary Accession #    Q15555 [Other Products]
 UniProt Secondary Accession #    Q9UQ33; B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6 [Other Products]
 UniProt Related Accession #    Q15555 [Other Products]
 Molecular Weight    30,691 Da
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 NCBI Official Full Name    microtubule-associated protein RP/EB family member 2 isoform 2
 NCBI Official Synonym Full Names    microtubule associated protein RP/EB family member 2
 NCBI Official Symbol    MAPRE2 [Similar Products]
 NCBI Official Synonym Symbols   
EB1; EB2; RP1; CSCSC2
[Similar Products]
 NCBI Protein Information    microtubule-associated protein RP/EB family member 2
 UniProt Protein Name    Microtubule-associated protein RP/EB family member 2
 UniProt Synonym Protein Names   
APC-binding protein EB2; End-binding protein 2; EB2
 Protein Family    Microtubule-associated protein RP/EB family
 UniProt Gene Name    MAPRE2 [Similar Products]
 UniProt Synonym Gene Names    RP1; EB2 [Similar Products]
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 NCBI Summary for MAPRE2    The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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 UniProt Comments for MAPRE2    RP1: shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Its function is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 18q12.1-q12.2

Cellular Component: cytoplasm; microtubule cytoskeleton

Molecular Function: identical protein binding; protein binding

Biological Process: cell proliferation; signal transduction

Disease: Skin Creases, Congenital Symmetric Circumferential, 2
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 Research Articles on MAPRE2    1. Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MAPRE2 antibodyDiseases associated with anti-MAPRE2 antibody
 Reference Product  PubMed Publications
 CLASP2 antibody  >1 publications with MAPRE2 and CLASP2
 Disease Name  Pubmed Publications
 Abnormalities, Drug-Induced Antibodies  >1 publications with MAPRE2 and Abnormalities, Drug-Induced
Organs/Tissues associated with anti-MAPRE2 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with MAPRE2 and Eye
 Blood Antibodies  >2 publications with MAPRE2 and Blood
 Lung Antibodies  >1 publications with MAPRE2 and Lung
 Intestine Antibodies  >1 publications with MAPRE2 and Intestine
 Nerve Antibodies  >1 publications with MAPRE2 and Nerve
 Kidney Antibodies  >1 publications with MAPRE2 and Kidney
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