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anti-MLANA antibody :: Rabbit anti-Human MART-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6013173 anti-MLANA antibody
Unit / Price
0.05 mg  /  $620 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MART-1 (MLANA), Polyclonal Antibody

 Also Known As   

MART-1, CT (Melanoma Antigen Recognized by T-cells 1, MART1, Antigen LB39-AA, Antigen SK29-AA, MLANA, Protein Melan-A)

 Product Synonym Names    Anti -MART-1, CT (Melanoma Antigen Recognized by T-cells 1, MART1, Antigen LB39-AA, Antigen SK29-AA, MLANA, Protein Melan-A)
 Product Gene Name   

anti-MLANA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (5890895..5909822). Location: 9p24.1
 OMIM    605513
 3D Structure    ModBase 3D Structure for Q16655
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human MLANA.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
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 Immunogen    Recombinant corresponding to human MLANA.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-MLANA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-MLANA antibody

   MART-1 (also known as Melan-A) is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.
 Product Categories/Family for anti-MLANA antibody    Antibodies; Abs to Cancer Markers
 Applications Tested/Suitable for anti-MLANA antibody   

Immunohistochemistry (IHC)

 Application Notes for anti-MLANA antibody    Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
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NCBI/Uniprot data below describe general gene information for MLANA. It may not necessarily be applicable to this product.
 NCBI GI #    5031913
 NCBI GeneID    2315
 NCBI Accession #    NP_005502.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005511.1 [Other Products]
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 UniProt Primary Accession #    Q16655 [Other Products]
 UniProt Secondary Accession #    Q6ICU4 [Other Products]
 UniProt Related Accession #    Q16655 [Other Products]
 Molecular Weight    13,157 Da [Similar Products]
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 NCBI Official Full Name    melanoma antigen recognized by T-cells 1
 NCBI Official Synonym Full Names    melan-A
 NCBI Official Symbol    MLANA [Similar Products]
 NCBI Official Synonym Symbols   
MART1; MART-1
[Similar Products]
 NCBI Protein Information    melanoma antigen recognized by T-cells 1; antigen LB39-AA; antigen SK29-AA; protein Melan-A
 UniProt Protein Name    Melanoma antigen recognized by T-cells 1
 UniProt Synonym Protein Names   
Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A
 Protein Family    Melanoma antigen recognized by T-cells
 UniProt Gene Name    MLANA [Similar Products]
 UniProt Synonym Gene Names    MART1; MART-1 [Similar Products]
 UniProt Entry Name    MAR1_HUMAN
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 UniProt Comments for MLANA    MLANA: Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; integral to plasma membrane; melanosome; trans-Golgi network

Molecular Function: protein binding
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 Research Articles on MLANA    1. melan A (A103) is not expressed in mesotheliomas
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MLANA antibodyDiseases associated with anti-MLANA antibody
 Reference Product  PubMed Publications
 HLA-A antibody  >354 publications with MLANA and HLA-A
 MAGEA3 antibody  >56 publications with MLANA and MAGEA3
 TYR antibody  >15 publications with MLANA and TYR
 TYRP1 antibody  >8 publications with MLANA and TYRP1
 DCT antibody  >2 publications with MLANA and DCT
 ITCH antibody  >2 publications with MLANA and ITCH
 GPR143 antibody  >2 publications with MLANA and GPR143
 SILV antibody  >2 publications with MLANA and SILV
 NEDD4 antibody  >1 publications with MLANA and NEDD4
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >949 publications with MLANA and Neoplasms
 Skin Diseases Antibodies  >339 publications with MLANA and Skin Diseases
 Skin Neoplasms Antibodies  >301 publications with MLANA and Skin Neoplasms
 Carcinoma Antibodies  >80 publications with MLANA and Carcinoma
 Neoplasms, Experimental Antibodies  >63 publications with MLANA and Neoplasms, Experimental
 Necrosis Antibodies  >49 publications with MLANA and Necrosis
 Eye Diseases Antibodies  >49 publications with MLANA and Eye Diseases
 Adenocarcinoma Antibodies  >36 publications with MLANA and Adenocarcinoma
 Nervous System Diseases Antibodies  >34 publications with MLANA and Nervous System Diseases
 Liver Neoplasms Antibodies  >27 publications with MLANA and Liver Neoplasms
Organs/Tissues associated with anti-MLANA antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >358 publications with MLANA and Skin
 Eye Antibodies  >34 publications with MLANA and Eye
 Kidney Antibodies  >31 publications with MLANA and Kidney
 Brain Antibodies  >21 publications with MLANA and Brain
 Ear Antibodies  >7 publications with MLANA and Ear
 Embryonic Tissue Antibodies  >6 publications with MLANA and Embryonic Tissue
 Mammary Gland Antibodies  >1 publications with MLANA and Mammary Gland
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