NP_001181883.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
matrin-3 isoform a
NCBI Official Synonym Full Names
matrin 3
NCBI Protein Information
matrin-3
UniProt Protein Name
Matrin-3
UniProt Synonym Gene Names
UniProt Entry Name
MATR3_HUMAN
NCBI Summary for MATR3
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]
UniProt Comments for MATR3
matrin 3: an acidic protein that is a component of the nuclear matrix. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.
Protein type: RNA processing; RNA-binding
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: nucleoplasm; nuclear matrix; membrane; nuclear inner membrane
Molecular Function: protein binding; zinc ion binding; nucleotide binding; structural molecule activity
Disease: Amyotrophic Lateral Sclerosis 21
Product References and Citations for anti-MATR3 antibody
Zeitz, M.J., et al. J. Cell. Biochem. 108(1):125-133(2009) Senderek, J., et al. Am. J. Hum. Genet. 84(4):511-518(2009) Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) : Malyavantham, K.S., et al. J. Cell. Biochem. 105(2):391-403(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Research Articles on MATR3
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Products associated with anti-MATR3 antibody
Diseases associated with anti-MATR3 antibody
Organs/Tissues associated with anti-MATR3 antibody
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