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anti-MD-1 antibody :: Rabbit MD-1 / LY86 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS240990
Unit / Price
0.05 mg  /  $605 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MD-1 / LY86, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human MD-1 / LY86

 Product Synonym Names    Anti-MD-1 / LY86 Antibody (Internal) IHC-plus; LY86; DJ80N2.1; Ly-86; MD1; MD-1; MD-1; RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1; Lymphocyte antigen 86; Human MD-1; LY86
 Product Gene Name   

anti-MD-1 antibody

[Similar Products]
 Product Synonym Gene Name    LY86 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605241
 3D Structure    ModBase 3D Structure for O95711
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Internal 15 amino acid peptide from human MD-1
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.02% sodium azide.
 Concentration    0.5 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    15 amino acid peptide from near the center of human MD-1.
 Immunogen    MD-1 / LY86 antibody was raised against 15 amino acid peptide from near the center of human MD-1.
 Antigen Modification    Internal
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 Preparation and Storage    Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-MD-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MD-1 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-MD-1 antibody    IHC-P (10 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-MD-1 antibody    Anti-LY86 / MD-1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-MD-1 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-MD-1 antibody    Western blot of MD-1 in Daudi cell lysate with MD-1 antibody at (A) 1 and (B) 2 g/ml.
anti-MD-1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MD-1. It may not necessarily be applicable to this product.
 NCBI GI #    4758708
 NCBI GeneID    9450
 NCBI Accession #    NP_004262.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004271.3 [Other Products]
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 UniProt Primary Accession #    O95711 [Other Products]
 UniProt Secondary Accession #    Q9UQC4 [Other Products]
 UniProt Related Accession #    O95711 [Other Products]
 Molecular Weight    17,906 Da
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 NCBI Official Full Name    lymphocyte antigen 86
 NCBI Official Synonym Full Names    lymphocyte antigen 86
 NCBI Official Symbol    LY86 [Similar Products]
 NCBI Official Synonym Symbols   
MD1; MD-1; MMD-1; dJ80N2.1
[Similar Products]
 NCBI Protein Information    lymphocyte antigen 86; ly-86; protein MD-1; MD-1, RP105-associated
 UniProt Protein Name    Lymphocyte antigen 86
 UniProt Synonym Protein Names   
Protein MD-1
 UniProt Gene Name    LY86 [Similar Products]
 UniProt Synonym Gene Names    MD1; Ly-86 [Similar Products]
 UniProt Entry Name    LY86_HUMAN
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 UniProt Comments for MD-1    LY86: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.

Protein type: Secreted; Secreted, signal peptide; Apoptosis

Chromosomal Location of Human Ortholog: 6p25.1

Cellular Component: extracellular space; plasma membrane

Biological Process: cell proliferation; apoptosis; positive regulation of lipopolysaccharide-mediated signaling pathway; innate immune response; inflammatory response; humoral immune response
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 Research Articles on MD-1    1. DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MD-1 antibodyPathways associated with anti-MD-1 antibody
 Reference Product  PubMed Publications
 TLR4 antibody  >23 publications with MD-1 and TLR4
 CD180 antibody  >12 publications with MD-1 and CD180
 CD14 antibody  >9 publications with MD-1 and CD14
 LY96 antibody  >8 publications with MD-1 and LY96
 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies  Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram
 Toll-Like Receptors Cascades Pathway antibodies  Toll-Like Receptors Cascades Pathway Diagram
Diseases associated with anti-MD-1 antibodyOrgans/Tissues associated with anti-MD-1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8 publications with MD-1 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with MD-1 and Disease Models, Animal
 Liver Diseases Antibodies  >3 publications with MD-1 and Liver Diseases
 Necrosis Antibodies  >3 publications with MD-1 and Necrosis
 Weight Loss Antibodies  >2 publications with MD-1 and Weight Loss
 Respiratory Tract Diseases Antibodies  >2 publications with MD-1 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >2 publications with MD-1 and Lung Diseases
 Cognition Disorders Antibodies  >1 publications with MD-1 and Cognition Disorders
 Fatty Liver Antibodies  >1 publications with MD-1 and Fatty Liver
 Poisoning Antibodies  >1 publications with MD-1 and Poisoning
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >6 publications with MD-1 and Spleen
 Vascular Antibodies  >3 publications with MD-1 and Vascular
 Lymph Node Antibodies  >2 publications with MD-1 and Lymph Node
 Placenta Antibodies  >1 publications with MD-1 and Placenta
 Intestine Antibodies  >1 publications with MD-1 and Intestine
 Pharynx Antibodies  >1 publications with MD-1 and Pharynx
 Bone Marrow Antibodies  >1 publications with MD-1 and Bone Marrow
 Lung Antibodies  >1 publications with MD-1 and Lung
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