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anti-MEST antibody :: Rabbit MEST Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS129580 anti-MEST antibody
Unit / Price
  DISCONTINUED
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MEST, Polyclonal Antibody

 Also Known As   

MEST Polyclonal Antibody

 Product Synonym Names    PEG1
 Product Gene Name   

anti-MEST antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601029
 3D Structure    ModBase 3D Structure for Q5EB52
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human MEST
 Calculated Molecular Weight    38kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-MEST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MEST antibody

   This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
 Product Categories/Family for anti-MEST antibody    Polyclonal
 Applications Tested/Suitable for anti-MEST antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-MEST antibody    WB: 1:200-1:2000
IHC: 1:50-1:200
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NCBI/Uniprot data below describe general gene information for MEST. It may not necessarily be applicable to this product.
 NCBI GI #    145566794
 NCBI GeneID    4232
 NCBI Accession #    Q5EB52.2 [Other Products]
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 UniProt Primary Accession #    Q5EB52 [Other Products]
 UniProt Secondary Accession #    O14973; O15007; Q6AI49; Q92571; B2R6S1 [Other Products]
 UniProt Related Accession #    Q5EB52 [Other Products]
 Molecular Weight    335
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 NCBI Official Full Name    Mesoderm-specific transcript homolog protein
 NCBI Official Synonym Full Names    mesoderm specific transcript
 NCBI Official Symbol    MEST [Similar Products]
 NCBI Official Synonym Symbols   
PEG1
[Similar Products]
 NCBI Protein Information    mesoderm-specific transcript homolog protein; paternally-expressed gene 1 protein
 UniProt Protein Name    Mesoderm-specific transcript homolog protein
 UniProt Synonym Protein Names   
Paternally-expressed gene 1 protein
 Protein Family    Mesoderm-specific transcript protein
 UniProt Gene Name    MEST [Similar Products]
 UniProt Synonym Gene Names    PEG1 [Similar Products]
 UniProt Entry Name    MEST_HUMAN
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 NCBI Summary for MEST    This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]
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 UniProt Comments for MEST    MEST: a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]

Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 3.-.-.-

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: hydrolase activity

Biological Process: response to retinoic acid; metabolic process; mesoderm development
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 Research Articles on MEST    1. altered DNA methylation at imprinted domains including IGF2/H19 and PEG1/MEST may mediate the association between human papillomavirus infection and invasive cervical cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MEST antibodyDiseases associated with anti-MEST antibody
 Reference Product  PubMed Publications
 GRB10 antibody  >21 publications with MEST and GRB10
 COPG2 antibody  >17 publications with MEST and COPG2
 CPA4 antibody  >3 publications with MEST and CPA4
 TSGA14 antibody  >3 publications with MEST and TSGA14
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >66 publications with MEST and Cardiovascular Diseases
 Heart Diseases Antibodies  >48 publications with MEST and Heart Diseases
 Kidney Diseases Antibodies  >35 publications with MEST and Kidney Diseases
 Brain Diseases Antibodies  >34 publications with MEST and Brain Diseases
 Disease Models, Animal Antibodies  >25 publications with MEST and Disease Models, Animal
 Pain Antibodies  >13 publications with MEST and Pain
 Infertility, Male Antibodies  >13 publications with MEST and Infertility, Male
 Adenocarcinoma Antibodies  >11 publications with MEST and Adenocarcinoma
 Death Antibodies  >11 publications with MEST and Death
 Edema Antibodies  >10 publications with MEST and Edema
Organs/Tissues associated with anti-MEST antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >126 publications with MEST and Blood
 Kidney Antibodies  >62 publications with MEST and Kidney
 Heart Antibodies  >51 publications with MEST and Heart
 Brain Antibodies  >44 publications with MEST and Brain
 Embryonic Tissue Antibodies  >40 publications with MEST and Embryonic Tissue
 Muscle Antibodies  >39 publications with MEST and Muscle
 Ear Antibodies  >39 publications with MEST and Ear
 Liver Antibodies  >32 publications with MEST and Liver
 Skin Antibodies  >29 publications with MEST and Skin
 Placenta Antibodies  >27 publications with MEST and Placenta
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