NP_001135906.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 130 kDa Predicted: 103 kDa
NCBI Official Full Name
protein O-GlcNAcase isoform b
NCBI Official Synonym Full Names
O-GlcNAcase
NCBI Protein Information
protein O-GlcNAcase
UniProt Protein Name
Protein O-GlcNAcase
UniProt Synonym Protein Names
Beta-N-acetylglucosaminidase1 PublicationManual assertion based on opinion iniRef.3"Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain."Gao Y., Wells L., Comer F.I., Parker G.J., Hart G.W.J. Biol. Chem. 276:9838-9845(2001) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, BIOPHYSICOCHEMICAL PROPERTIES, ACTIVITY REGULATION, IDENTIFICATION BY MASS SPECTROMETRY.
UniProt Synonym Gene Names
OGA1 PublicationManual assertion based on opinion iniRef.15; NCOAT [Similar Products]
NCBI Summary for MGEA5
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
UniProt Comments for MGEA5
Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714).
Research Articles on MGEA5
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Products associated with anti-MGEA5 antibody
Pathways associated with anti-MGEA5 antibody
Diseases associated with anti-MGEA5 antibody
Organs/Tissues associated with anti-MGEA5 antibody
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