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anti-MGST3 antibody :: Rabbit anti-Human MGST3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7052149
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MGST3, Polyclonal Antibody

★Popular Item★
 Also Known As   

MGST3 Antibody

 Product Synonym Names    Microsomal glutathione S-transferase 3; Microsomal GST-3; Microsomal GST-III; MGST3
 Product Gene Name   

anti-MGST3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF026977 mRNA
 3D Structure    ModBase 3D Structure for O14880
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Microsomal glutathione S-transferase 3 protein (30-70AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MGST3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MGST3 antibody

   Also functions as a glutathione peroxidase.
 Applications Tested/Suitable for anti-MGST3 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-MGST3 antibody    WB: 1:500-1:5000
IF: 1:50-1:200
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 Western Blot (WB) of anti-MGST3 antibody    Western Blot
Positive WB detected in: PC3 whole cell lysate
All lanes: MGST3 antibody at 3.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 17 KDa
Observed band size: 17 KDa

anti-MGST3 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-MGST3 antibody    Immunofluorescent analysis of PC3 cells using MBS7052149 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-MGST3 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for MGST3. It may not necessarily be applicable to this product.
 NCBI GI #    4758714
 NCBI GeneID    4259
 NCBI Accession #    NP_004519.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004528.3 [Other Products]
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 UniProt Primary Accession #    O14880 [Other Products]
 UniProt Secondary Accession #    Q6ICN4; B2R592 [Other Products]
 UniProt Related Accession #    O14880 [Other Products]
 Molecular Weight    16,516 Da
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 NCBI Official Full Name    microsomal glutathione S-transferase 3
 NCBI Official Synonym Full Names    microsomal glutathione S-transferase 3
 NCBI Official Symbol    MGST3 [Similar Products]
 NCBI Official Synonym Symbols   
GST-III
[Similar Products]
 NCBI Protein Information    microsomal glutathione S-transferase 3
 UniProt Protein Name    Microsomal glutathione S-transferase 3
 UniProt Synonym Protein Names   
Microsomal GST-III
 Protein Family    Microsomal glutathione S-transferase
 UniProt Gene Name    MGST3 [Similar Products]
 UniProt Synonym Gene Names    Microsomal GST-3 [Similar Products]
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 NCBI Summary for MGST3    This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011]
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 UniProt Comments for MGST3    MGST3: Also functions as a glutathione peroxidase. Belongs to the MAPEG family.

Protein type: EC 2.5.1.18; Membrane protein, integral; Membrane protein, multi-pass; Other Amino Acids Metabolism - glutathione; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 1q24.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; nuclear envelope

Molecular Function: glutathione peroxidase activity; glutathione transferase activity; peroxidase activity; protein binding

Biological Process: lipid metabolic process; signal transduction; xenobiotic metabolic process
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 Research Articles on MGST3    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MGST3 antibodyDiseases associated with anti-MGST3 antibody
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >8 publications with MGST3 and Drug Toxicity
 Inflammation Antibodies  >7 publications with MGST3 and Inflammation
 Cardiovascular Diseases Antibodies  >4 publications with MGST3 and Cardiovascular Diseases
 Liver Diseases Antibodies  >3 publications with MGST3 and Liver Diseases
 Neoplasms Antibodies  >2 publications with MGST3 and Neoplasms
 Necrosis Antibodies  >2 publications with MGST3 and Necrosis
 Hepatitis Antibodies  >1 publications with MGST3 and Hepatitis
 Kidney Diseases Antibodies  >1 publications with MGST3 and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with MGST3 and Fatty Liver
 Heart Diseases Antibodies  >1 publications with MGST3 and Heart Diseases
Organs/Tissues associated with anti-MGST3 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with MGST3 and Kidney
 Intestine Antibodies  >3 publications with MGST3 and Intestine
 Brain Antibodies  >3 publications with MGST3 and Brain
 Embryonic Tissue Antibodies  >2 publications with MGST3 and Embryonic Tissue
 Heart Antibodies  >1 publications with MGST3 and Heart
 Adrenal Gland Antibodies  >1 publications with MGST3 and Adrenal Gland
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