NP_001291493.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,631 Da
NCBI Official Full Name
mitochondrial dynamics protein MID51 isoform 2
NCBI Official Synonym Full Names
mitochondrial elongation factor 1
NCBI Official Synonym Symbols
MID51; SMCR7L; HSU79252; dJ1104E15.3 [Similar Products]
NCBI Protein Information
mitochondrial dynamics protein MID51
UniProt Protein Name
Mitochondrial dynamics protein MID51
UniProt Synonym Protein Names
Mitochondrial dynamics protein of 51 kDa; Mitochondrial elongation factor 1; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; SMCR7-like protein
UniProt Synonym Gene Names
UniProt Entry Name
MID51_HUMAN
UniProt Comments for MIEF1
Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.
Research Articles on MIEF1
Precautions
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Disclaimer
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Products associated with anti-MIEF1 antibody
Diseases associated with anti-MIEF1 antibody
Organs/Tissues associated with anti-MIEF1 antibody
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