Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow MMP9 rightarrow Polyclonal MMP9  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Transforming Growth Factor Beta 3 (TGFb3) Recombinant Protein
 • PTHR2 ELISA Kit
 • Hemoglobin (HB) Native Protein
 • Elafin-PI3 ELISA Kit
 • Cystatin 3 (CST3) Recombinant Protein
 • Interleukin 26 (IL26) CLIA Kit
 • TRAIL R3 (TRAIL-R3) ELISA Kit
 • Peroxisome Proliferator-activated Receptor beta (PPAR-beta) ELISA Kit
 • palmitoyl-protein thioesterase 1 (PPT1) ELISA Kit
 • Hexokinase-2 (HK-2) Recombinant Protein
 • EGFR Antibody
 • Glycophorin A (GYPA) ELISA Kit
 • chromosome 9 open reading frame 47 (C9orf47) ELISA Kit
 • STELLAR Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-MMP9 antibody :: Rabbit anti-Human MMP9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS535668 anti-MMP9 antibody
Unit / Price
0.05 mg  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MMP9, Polyclonal Antibody

 Also Known As   

MMP9 antibody

 Product Synonym Names    Polyclonal MMP9; Anti-MMP9; gelatinase b; matrix metalloproteinase 9; MMP 9; MMP -9; MMP9; 92 kd type iv collagenase; mmp9; 92kd gelatinase
 Product Gene Name   

anti-MMP9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    120361
 3D Structure    ModBase 3D Structure for P14780
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    MMP9 antibody was purified by affinity chromatography.
 Form/Format    Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
 Concentration    1.0 mg/ml (lot specific)
Section Bar
 Biological Significance    Matrix metallopeptidase 9 (MMP9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakDaown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
 Immunogen    MMP9 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
Section Bar
 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-MMP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-MMP9 antibody

   Rabbit polyclonal MMP9 antibody
 Product Categories/Family for anti-MMP9 antibody    Proteases, Inhibitors, & Enzymes
 Applications Tested/Suitable for anti-MMP9 antibody   

Immunohistochemistry (IHC) Paraffin

 Application Notes for anti-MMP9 antibody    IHC-P: 10 ug/ml
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for MMP9. It may not necessarily be applicable to this product.
 NCBI GI #    74272287
 NCBI GeneID    4318
 NCBI Accession #    NP_004985 [Other Products]
 NCBI GenBank Nucleotide #    NM_004994.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P14780 [Other Products]
 UniProt Secondary Accession #    Q3LR70; Q8N725; Q9H4Z1; Q9UCJ9; Q9UCL1; Q9UDK2; B2R7V9 [Other Products]
 UniProt Related Accession #    P14780 [Other Products]
 Molecular Weight    78,458 Da
Table BarTOPTable Bar
 NCBI Official Full Name    matrix metalloproteinase-9 preproprotein
 NCBI Official Synonym Full Names    matrix metallopeptidase 9
 NCBI Official Symbol    MMP9 [Similar Products]
 NCBI Official Synonym Symbols   
GELB; CLG4B; MMP-9; MANDP2
[Similar Products]
 NCBI Protein Information    matrix metalloproteinase-9
 UniProt Protein Name    Matrix metalloproteinase-9
 UniProt Synonym Protein Names   
92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
 Protein Family    Matrix metalloproteinase
 UniProt Gene Name    MMP9 [Similar Products]
 UniProt Synonym Gene Names    CLG4B; MMP-9; GELB [Similar Products]
 UniProt Entry Name    MMP9_HUMAN
Section Bar
 NCBI Summary for MMP9    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for MMP9    MMP9: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. Activated by 4-aminophenylmercuric acetate and phorbol ester. Up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. Produced by normal alveolar macrophages and granulocytes. Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. Belongs to the peptidase M10A family.

Protein type: Protease; Motility/polarity/chemotaxis; EC 3.4.24.35; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: collagen binding; identical protein binding; protein binding; zinc ion binding; metalloendopeptidase activity; endopeptidase activity

Biological Process: positive regulation of keratinocyte migration; axon guidance; extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; ossification; macrophage differentiation; positive regulation of apoptosis; ephrin receptor signaling pathway; proteolysis; leukocyte migration; skeletal development; embryo implantation

Disease: Metaphyseal Anadysplasia 2
Table BarTOPTable Bar
 Research Articles on MMP9    1. Abeta25-35 can induce the release from human neutrophils of pro-MMP-9, a metalloprotease involved in the onset of inflammation
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-MMP9 antibodyPathways associated with anti-MMP9 antibody
 Reference Product  PubMed Publications
 JUN antibody  >414 publications with MMP9 and JUN
 TIMP1 antibody  >328 publications with MMP9 and TIMP1
 TIMP2 antibody  >191 publications with MMP9 and TIMP2
 TGFB1 antibody  >136 publications with MMP9 and TGFB1
 SRC antibody  >54 publications with MMP9 and SRC
 CD44 antibody  >38 publications with MMP9 and CD44
 THBS1 antibody  >23 publications with MMP9 and THBS1
 NFKB1 antibody  >11 publications with MMP9 and NFKB1
 PLG antibody  >8 publications with MMP9 and PLG
 FOSL1 antibody  >4 publications with MMP9 and FOSL1
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
Diseases associated with anti-MMP9 antibodyOrgans/Tissues associated with anti-MMP9 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >605 publications with MMP9 and Inflammation
 Neoplasm Invasiveness Antibodies  >517 publications with MMP9 and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >445 publications with MMP9 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >205 publications with MMP9 and Breast Neoplasms
 Liver Diseases Antibodies  >173 publications with MMP9 and Liver Diseases
 Carcinoma, Squamous Cell Antibodies  >120 publications with MMP9 and Carcinoma, Squamous Cell
 Aortic Diseases Antibodies  >113 publications with MMP9 and Aortic Diseases
 Aortic Aneurysm Antibodies  >105 publications with MMP9 and Aortic Aneurysm
 Carcinoma, Hepatocellular Antibodies  >92 publications with MMP9 and Carcinoma, Hepatocellular
 Aortic Aneurysm, Abdominal Antibodies  >85 publications with MMP9 and Aortic Aneurysm, Abdominal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >947 publications with MMP9 and Blood
 Lung Antibodies  >414 publications with MMP9 and Lung
 Bone Antibodies  >372 publications with MMP9 and Bone
 Brain Antibodies  >327 publications with MMP9 and Brain
 Liver Antibodies  >253 publications with MMP9 and Liver
 Bone Marrow Antibodies  >147 publications with MMP9 and Bone Marrow
 Connective Tissue Antibodies  >146 publications with MMP9 and Connective Tissue
 Lymph Node Antibodies  >146 publications with MMP9 and Lymph Node
 Kidney Antibodies  >139 publications with MMP9 and Kidney
 Embryonic Tissue Antibodies  >127 publications with MMP9 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions