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anti-MNDA antibody :: anti-Human MNDA Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8200140
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MNDA, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-MNDA Antibody

 Product Synonym Names    Myeloid cell nuclear differentiation antigen
 Product Gene Name   

anti-MNDA antibody

[Similar Products]
 Antibody/Peptide Pairs    MNDA peptide (MBS8202049) is used for blocking the activity of MNDA antibody (MBS8200140)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    159553
 3D Structure    ModBase 3D Structure for P41218
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 Clonality    Polyclonal
 Species Reactivity    Human
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 Specificity    Recognizes endogenous levels of MNDA protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MNDA. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4C. Upon delivery aliquot and store at -20C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-MNDA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-MNDA antibody

   Rabbit polyclonal antibody to MNDA
 Applications Tested/Suitable for anti-MNDA antibody   

WB, IH

 Application Notes for anti-MNDA antibody    WB (1/500 - 1/1000)
IH(1/100 - 1/200)
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 Western Blot (WB) of anti-MNDA antibody    Western blot analysis of MNDA expression in THP1 (A) whole cell lysates.
anti-MNDA antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-MNDA antibody    Immunohistochemical analysis of MNDA staining in human lymph node formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-MNDA antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MNDA. It may not necessarily be applicable to this product.
 NCBI GI #    4505227
 NCBI GeneID    4332
 NCBI Accession #    NP_002423.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002432.1 [Other Products]
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 UniProt Primary Accession #    P41218 [Other Products]
 UniProt Related Accession #    P41218 [Other Products]
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 NCBI Official Full Name    myeloid cell nuclear differentiation antigen
 NCBI Official Synonym Full Names    myeloid cell nuclear differentiation antigen
 NCBI Official Symbol    MNDA [Similar Products]
 NCBI Official Synonym Symbols   
PYHIN3
[Similar Products]
 NCBI Protein Information    myeloid cell nuclear differentiation antigen
 UniProt Protein Name    Myeloid cell nuclear differentiation antigen
 Protein Family    Myeloid cell nuclear differentiation antigen
 UniProt Gene Name    MNDA [Similar Products]
 UniProt Entry Name    MNDA_HUMAN
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 NCBI Summary for MNDA    The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MNDA    May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
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 Research Articles on MNDA    1. Studied the HIN domain of recombinant myeloid nuclear differentiation antigen (MNDA).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MNDA antibodyDiseases associated with anti-MNDA antibody
 Reference Product  PubMed Publications
 YY1 antibody  >1 publications with MNDA and YY1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with MNDA and Inflammation
 Hematologic Diseases Antibodies  >6 publications with MNDA and Hematologic Diseases
 Chromosome Aberrations Antibodies  >5 publications with MNDA and Chromosome Aberrations
 Breast Neoplasms Antibodies  >3 publications with MNDA and Breast Neoplasms
 Disease Models, Animal Antibodies  >2 publications with MNDA and Disease Models, Animal
 Kidney Diseases Antibodies  >2 publications with MNDA and Kidney Diseases
 Learning Disorders Antibodies  >1 publications with MNDA and Learning Disorders
 Weight Loss Antibodies  >1 publications with MNDA and Weight Loss
 Cardiovascular Diseases Antibodies  >1 publications with MNDA and Cardiovascular Diseases
 Atherosclerosis Antibodies  >1 publications with MNDA and Atherosclerosis
Organs/Tissues associated with anti-MNDA antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >26 publications with MNDA and Blood
 Bone Antibodies  >8 publications with MNDA and Bone
 Bone Marrow Antibodies  >8 publications with MNDA and Bone Marrow
 Brain Antibodies  >6 publications with MNDA and Brain
 Kidney Antibodies  >4 publications with MNDA and Kidney
 Spleen Antibodies  >2 publications with MNDA and Spleen
 Vascular Antibodies  >2 publications with MNDA and Vascular
 Eye Antibodies  >1 publications with MNDA and Eye
 Lung Antibodies  >1 publications with MNDA and Lung
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