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anti-MTBP antibody :: Rabbit anti-Human, Mouse MTBP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2524074
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MTBP, Polyclonal Antibody

★Popular Item★
 Also Known As   

MTBP Polyclonal Antibody

 Product Synonym Names    MDM2BP
 Product Gene Name   

anti-MTBP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605927
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
 Concentration    1.2mg/mL (lot specific)
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-MTBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-MTBP antibody

   Background: This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation.
 Product Categories/Family for anti-MTBP antibody    Cell biology
 Applications Tested/Suitable for anti-MTBP antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-MTBP antibody    IHC: 1:25-1:100
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 Immunohistochemistry (IHC) of anti-MTBP antibody    Immunohistochemistry of paraffin-embedded Human brain tissue using MTBP Polyclonal Antibody at dilution 1:20
anti-MTBP antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-MTBP antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MTBP Polyclonal Antibody at dilution 1:20
anti-MTBP antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MTBP. It may not necessarily be applicable to this product.
 NCBI GI #    21630257
 NCBI GeneID    27085
 NCBI Accession #    NP_071328.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022045.4 [Other Products]
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 UniProt Secondary Accession #    Q9HA89; B4DUR5 [Other Products]
 UniProt Related Accession #    Q96DY7 [Other Products]
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 NCBI Official Full Name    mdm2-binding protein
 NCBI Official Synonym Full Names    MDM2 binding protein
 NCBI Official Symbol    MTBP [Similar Products]
 NCBI Official Synonym Symbols   
MDM2BP
[Similar Products]
 NCBI Protein Information    mdm2-binding protein; MDM2 (mouse double minute 2)-binding protein, 104kD; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa
 UniProt Protein Name    Mdm2-binding protein
 Protein Family    Mdm2-binding protein
 UniProt Gene Name    MTBP [Similar Products]
 UniProt Synonym Gene Names    hMTBP [Similar Products]
 UniProt Entry Name    MTBP_HUMAN
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 NCBI Summary for MTBP    This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]
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 UniProt Comments for MTBP    MTBP: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Belongs to the MTBP family.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 8q24.12

Cellular Component: kinetochore; chromatin

Biological Process: negative regulation of cell proliferation; traversing start control point of mitotic cell cycle; negative regulation of mitosis; cell cycle arrest
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 Research Articles on MTBP    1. MTBP associated with MYC at promoters and increased MYC-mediated transcription, proliferation, neoplastic transformation, and tumor development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MTBP antibodyDiseases associated with anti-MTBP antibody
 Reference Product  PubMed Publications
 MDM2 antibody  >17 publications with MTBP and MDM2
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with MTBP and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with MTBP and Disease Models, Animal
 Lymphoma Antibodies  >1 publications with MTBP and Lymphoma
 Liver Neoplasms Antibodies  >1 publications with MTBP and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with MTBP and Liver Diseases
 Necrosis Antibodies  >1 publications with MTBP and Necrosis
 Neoplasms, Experimental Antibodies  >1 publications with MTBP and Neoplasms, Experimental
 Mammary Neoplasms, Animal Antibodies  >1 publications with MTBP and Mammary Neoplasms, Animal
Organs/Tissues associated with anti-MTBP antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >2 publications with MTBP and Embryonic Tissue
 Placenta Antibodies  >2 publications with MTBP and Placenta
 Eye Antibodies  >1 publications with MTBP and Eye
 Larynx Antibodies  >1 publications with MTBP and Larynx
 Liver Antibodies  >1 publications with MTBP and Liver
 Connective Tissue Antibodies  >1 publications with MTBP and Connective Tissue
 Lymph Node Antibodies  >1 publications with MTBP and Lymph Node
 Mammary Gland Antibodies  >1 publications with MTBP and Mammary Gland
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