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anti-MTCH1 antibody :: Rabbit anti-Human MTCH1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044757
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MTCH1, Polyclonal Antibody

★Popular Item★
 Also Known As   

MTCH1 Antibody

 Product Synonym Names    Mitochondrial carrier homolog 1; Presenilin-associated protein; MTCH1; PSAP; CGI-64; UNQ1871/PRO4314
 Product Gene Name   

anti-MTCH1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    610449
 3D Structure    ModBase 3D Structure for Q9NZJ7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Mitochondrial carrier homolog 1 protein (100-250AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133799
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MTCH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MTCH1 antibody

   Potential mitochondrial transporter. May play a role in apoptosis.
 Applications Tested/Suitable for anti-MTCH1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-MTCH1 antibody    Western blot
All lanes:  MTCH1antibody at 2.32ug/ml
Lane 1 : MCF7 whole cell lysate
Lane 2 : HepG-2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 42,40,20 kDa
Observed band size: 42 kDa

anti-MTCH1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-MTCH1 antibody    Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044757 at dilution 1:100
anti-MTCH1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-MTCH1 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044757 at dilution 1:100
anti-MTCH1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MTCH1. It may not necessarily be applicable to this product.
 NCBI GI #    410442521
 NCBI GeneID    23787
 NCBI Accession #    NP_001258570.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271641.1 [Other Products]
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 UniProt Primary Accession #    Q9NZJ7 [Other Products]
 UniProt Secondary Accession #    Q6PK60; Q6UX45; Q7L465; Q9BW23; Q9NZR6; Q9UJZ5; A8KAX5; B2RCE3 [Other Products]
 UniProt Related Accession #    Q9NZJ7 [Other Products]
 Molecular Weight    19,058 Da
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 NCBI Official Full Name    mitochondrial carrier homolog 1 PSAP-LL
 NCBI Official Synonym Full Names    mitochondrial carrier 1
 NCBI Official Symbol    MTCH1 [Similar Products]
 NCBI Official Synonym Symbols   
PSAP; PIG60; CGI-64; SLC25A49
[Similar Products]
 NCBI Protein Information    mitochondrial carrier homolog 1
 UniProt Protein Name    Mitochondrial carrier homolog 1
 UniProt Synonym Protein Names   
Presenilin-associated protein
 Protein Family    Mitochondrial carrier
 UniProt Gene Name    MTCH1 [Similar Products]
 UniProt Synonym Gene Names    PSAP [Similar Products]
 UniProt Entry Name    MTCH1_HUMAN
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 NCBI Summary for MTCH1    This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]
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 UniProt Comments for MTCH1    MTCH1: Potential mitochondrial transporter. May play a role in apoptosis. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.2

Cellular Component: membrane; mitochondrion

Molecular Function: protein binding

Biological Process: caspase activation; positive regulation of apoptosis
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 Research Articles on MTCH1    1. Results indicate that EGR-1 is a transcriptional regulator of MTCH1 and give some clues about the cellular processes in which MTCH1 might participate.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-MTCH1 antibodyOrgans/Tissues associated with anti-MTCH1 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with MTCH1 and Breast Neoplasms
 Brain Diseases Antibodies  >1 publications with MTCH1 and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with MTCH1 and Disease Models, Animal
 Cognition Disorders Antibodies  >1 publications with MTCH1 and Cognition Disorders
 Memory Disorders Antibodies  >1 publications with MTCH1 and Memory Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with MTCH1 and Brain
 Blood Antibodies  >2 publications with MTCH1 and Blood
 Nerve Antibodies  >1 publications with MTCH1 and Nerve
 Muscle Antibodies  >1 publications with MTCH1 and Muscle
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