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anti-MUC12 antibody :: Rabbit MUC12 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS194309 anti-MUC12 antibody
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MUC12, Polyclonal Antibody

 Also Known As   

MUC12 Polyclonal Antibody

 Product Synonym Names    MUC12
 Product Gene Name   

anti-MUC12 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 7; NC_000007.13 (100612904..100662230). Location: 7q22
 OMIM    604609
 3D Structure    ModBase 3D Structure for Q9UKN1
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 Clonality    Polyclonal
 Host    Rabbit
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 Specificity    MUC12 [This rabbit antibody recognizes aa 10-24 of human MUC12 (Mucin 12), a novel mucin that appears to be involved in epithelial cell growth regulation.]
This antibody recognizes human MUC12 (Mucin 12), a novel mucin that appears to be involved in epithelial cell growth regulation. MUC12 is downregulated in colorectal cancers.
 Form/Format    100 ug IgG in 100 ul PBS, pH 7.4, purified by immunoaffinity chromatography.
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 Antigen    Peptide corresponding to aa 0-24 of human Mucin 12.
 Stabilizer    None
 Preservatives    0.02% sodium azide
 Dilutions Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of anti-MUC12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MUC12 antibody    Cancer Research Products
 Applications Tested/Suitable for anti-MUC12 antibody   

Immunoblot

 Application Notes for anti-MUC12 antibody    Immunoblotting: use at 1:500-1:1,000 dilution.
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NCBI/Uniprot data below describe general gene information for MUC12. It may not necessarily be applicable to this product.
 NCBI GI #    256600257
 NCBI GeneID    10071
 NCBI Accession #    NP_001157934.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164462.1 [Other Products]
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 UniProt Primary Accession #    Q9UKN1 [Other Products]
 UniProt Secondary Accession #    Q9UKN0; A6ND38 [Other Products]
 UniProt Related Accession #    Q9UKN1 [Other Products]
 Molecular Weight    558,164 Da [Similar Products]
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 NCBI Official Full Name    mucin-12
 NCBI Official Synonym Full Names    mucin 12, cell surface associated
 NCBI Official Symbol    MUC12 [Similar Products]
 NCBI Official Synonym Symbols   
MUC11; MUC-11; MUC-12
[Similar Products]
 NCBI Protein Information    mucin-12; mucin 11; mucin-11; OTTHUMP00000211374
 UniProt Protein Name    Mucin-12
 UniProt Synonym Protein Names   
Mucin-11
 Protein Family    Mucin
 UniProt Gene Name    MUC12 [Similar Products]
 UniProt Synonym Gene Names    MUC11 [Similar Products]
 UniProt Entry Name    MUC12_HUMAN
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 UniProt Comments for MUC12    MUC12: Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: Golgi lumen; integral to plasma membrane

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; regulation of cell growth; post-translational protein modification
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 Research Articles on MUC12    1. Multivariate analysis disclosed that MUC12 expression status was an independent prognostic factor in Stages II and III CRC (relative risk, 8.236; 95% confidence interval, 1.702-39.849 p = 0.009).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MUC12 antibodyOrgans/Tissues associated with anti-MUC12 antibody
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Termination Of O-glycan Biosynthesis Pathway antibodies  Termination Of O-glycan Biosynthesis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >9 publications with MUC12 and Intestine
 Kidney Antibodies  >1 publications with MUC12 and Kidney
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