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anti-MYCBP antibody :: Rabbit MYCBP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS129245
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MYCBP, Polyclonal Antibody

 Also Known As   

MYCBP Polyclonal Antibody

 Product Synonym Names    AMY-1
 Product Gene Name   

anti-MYCBP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606535
 3D Structure    ModBase 3D Structure for Q99417
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human MYCBP
 Calculated Molecular Weight    12kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-MYCBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MYCBP antibody

   The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
 Product Categories/Family for anti-MYCBP antibody    Polyclonal
 Applications Tested/Suitable for anti-MYCBP antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-MYCBP antibody    WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
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 Western Blot (WB) of anti-MYCBP antibody    Western blot analysis of extracts of various cell lines, using MYCBP antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
anti-MYCBP antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MYCBP. It may not necessarily be applicable to this product.
 NCBI GI #    33112671
 NCBI GeneID    26292
 NCBI Accession #    Q99417.3 [Other Products]
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 UniProt Primary Accession #    Q99417 [Other Products]
 UniProt Secondary Accession #    Q5TA64; Q96HE2; B2R4N0 [Other Products]
 UniProt Related Accession #    Q99417 [Other Products]
 Molecular Weight    103
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 NCBI Official Full Name    C-Myc-binding protein
 NCBI Official Synonym Full Names    MYC binding protein
 NCBI Official Symbol    MYCBP [Similar Products]
 NCBI Official Synonym Symbols   
AMY-1
[Similar Products]
 NCBI Protein Information    C-Myc-binding protein; associate of myc-1; c-myc binding protein
 UniProt Protein Name    C-Myc-binding protein
 UniProt Synonym Protein Names   
Associate of Myc 1; AMY-1
 Protein Family    MYCBP-associated protein
 UniProt Gene Name    MYCBP [Similar Products]
 UniProt Synonym Gene Names    AMY1; AMY-1 [Similar Products]
 UniProt Entry Name    MYCBP_HUMAN
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 NCBI Summary for MYCBP    The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for MYCBP    MYCBP: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. Belongs to the AMY1 family.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1p33-p32.2

Cellular Component: centrosome; mitochondrion; cytoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spermatogenesis
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 Research Articles on MYCBP    1. c-Myc expression is reduced in pterygium compared with normal conjunctiva.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MYCBP antibodyPathways associated with anti-MYCBP antibody
 Reference Product  PubMed Publications
 MYC antibody  >75 publications with MYCBP and MYC
 AKAP1 antibody  >3 publications with MYCBP and AKAP1
 ARFGEF1 antibody  >1 publications with MYCBP and ARFGEF1
 MYCBPAP antibody  >1 publications with MYCBP and MYCBPAP
 C3orf15 antibody  >1 publications with MYCBP and C3orf15
 Products by Pathway  Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
Diseases associated with anti-MYCBP antibodyOrgans/Tissues associated with anti-MYCBP antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >9 publications with MYCBP and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >7 publications with MYCBP and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >5 publications with MYCBP and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >4 publications with MYCBP and Liver Neoplasms
 Adenocarcinoma Antibodies  >3 publications with MYCBP and Adenocarcinoma
 Hyperplasia Antibodies  >3 publications with MYCBP and Hyperplasia
 Liver Diseases Antibodies  >3 publications with MYCBP and Liver Diseases
 Prostatic Diseases Antibodies  >3 publications with MYCBP and Prostatic Diseases
 Urinary Bladder Neoplasms Antibodies  >2 publications with MYCBP and Urinary Bladder Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with MYCBP and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >7 publications with MYCBP and Liver
 Bone Antibodies  >5 publications with MYCBP and Bone
 Lymph Node Antibodies  >5 publications with MYCBP and Lymph Node
 Prostate Antibodies  >5 publications with MYCBP and Prostate
 Stomach Antibodies  >4 publications with MYCBP and Stomach
 Blood Antibodies  >4 publications with MYCBP and Blood
 Bone Marrow Antibodies  >3 publications with MYCBP and Bone Marrow
 Vascular Antibodies  >3 publications with MYCBP and Vascular
 Embryonic Tissue Antibodies  >3 publications with MYCBP and Embryonic Tissue
 Testis Antibodies  >3 publications with MYCBP and Testis
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