P10166
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Mycl1 protein
NCBI Official Synonym Full Names
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
NCBI Official Synonym Symbols
L-myc; Lmyc1; Lmyc-1; bHLHe38; AW536278; MGC102165 [Similar Products]
NCBI Protein Information
protein L-Myc-1; OTTMUSP00000009305; OTTMUSP00000009306; L-myc-1 proto-oncogene protein; lung carcinoma myc related oncogene 1
UniProt Protein Name
Protein L-Myc-1
UniProt Synonym Gene Names
UniProt Entry Name
MYCL1_MOUSE
NCBI Summary for Mycl1
This gene encodes a basic helix-loop-helix leucine zipper (bHLHZip) protein that heterodimerizes with another bHLHZip protein to drive transcription of targets important for proliferation, apoptosis and differentiation. Mice lacking this gene product show marked decrease in T-cell priming during bacterial and viral infections. In humans, this gene was found to be amplified in small-cell lung cancers. Alternate splicing of this gene results in multiple variants. [provided by RefSeq, Dec 2014]
UniProt Comments for Mycl1
L-Myc: a proto-oncogenic transcription factor. Targets include CCL6 chemokine gene. Plays a role in cell proliferation, apoptosis and in the development of human tumors.
Protein type: DNA-binding; Transcription factor; Oncoprotein
Cellular Component: nucleus
Molecular Function: protein dimerization activity; protein binding; DNA binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent
Research Articles on Mycl1
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Diseases associated with anti-Mycl1 antibody
Organs/Tissues associated with anti-Mycl1 antibody
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