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anti-MYO3A antibody :: Rabbit anti-Human, Mouse MYO3A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8530231 anti-MYO3A antibody
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MYO3A, Polyclonal Antibody

★Popular Item★
 Also Known As   

MYO3A Polyclonal Antibody

 Product Synonym Names    Myosin-IIIa; EC 2.7.11.1; MYO3A
 Product Gene Name   

anti-MYO3A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606808
 3D Structure    ModBase 3D Structure for Q8NEV4
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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 Immunogen    Synthesized peptide derived from human protein. at AA range: 180-260
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-MYO3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MYO3A antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-MYO3A antibody    WB: 1:500-2000
ELISA: 1:5000-20000
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NCBI/Uniprot data below describe general gene information for MYO3A. It may not necessarily be applicable to this product.
 NCBI GI #    145275208
 NCBI GeneID    53904
 NCBI Accession #    NP_059129.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_017433.4 [Other Products]
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 UniProt Primary Accession #    Q8NEV4 [Other Products]
 UniProt Secondary Accession #    Q4G0X2; Q5VZ28; Q8WX17; Q9NYS8 [Other Products]
 UniProt Related Accession #    Q8NEV4 [Other Products]
 Molecular Weight    177
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 NCBI Official Full Name    myosin-IIIa
 NCBI Official Synonym Full Names    myosin IIIA
 NCBI Official Symbol    MYO3A [Similar Products]
 NCBI Official Synonym Symbols   
DFNB30
[Similar Products]
 NCBI Protein Information    myosin-IIIa
 UniProt Protein Name    Myosin-IIIa
 Protein Family    Myosin
 UniProt Gene Name    MYO3A [Similar Products]
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 NCBI Summary for MYO3A    The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MYO3A    Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing (PubMed:12032315). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments ().
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 Research Articles on MYO3A    1. MYO3A is more efficient than MYO3B at increasing formation and elongation of stable microvilli on the surface of cultured epithelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-MYO3A antibodyOrgans/Tissues associated with anti-MYO3A antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with MYO3A and Nervous System Diseases
 Gastrointestinal Diseases Antibodies  >1 publications with MYO3A and Gastrointestinal Diseases
 Brain Diseases Antibodies  >1 publications with MYO3A and Brain Diseases
 Vision Disorders Antibodies  >1 publications with MYO3A and Vision Disorders
 Central Nervous System Diseases Antibodies  >1 publications with MYO3A and Central Nervous System Diseases
 Blindness Antibodies  >1 publications with MYO3A and Blindness
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >5 publications with MYO3A and Eye
 Brain Antibodies  >3 publications with MYO3A and Brain
 Testis Antibodies  >2 publications with MYO3A and Testis
 Kidney Antibodies  >1 publications with MYO3A and Kidney
 Pancreas Antibodies  >1 publications with MYO3A and Pancreas
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