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anti-MYPT1 antibody :: Rabbit MYPT1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2536665
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MYPT1, Polyclonal Antibody

★Popular Item★
 Also Known As   

MYPT1 Polyclonal Antibody

 Product Synonym Names    PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit
 Product Gene Name   

anti-MYPT1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from human MYPT1 around the non-phosphorylation site of T696.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MYPT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MYPT1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-MYPT1 antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-MYPT1 antibody    Western Blot analysis of various cells using MYPT1 Polyclonal Antibody at dilution of 1:2000.
anti-MYPT1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MYPT1. It may not necessarily be applicable to this product.
 NCBI GI #    13365495
 NCBI GeneID    17931
 NCBI Accession #    BAB39108.1 [Other Products]
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 UniProt Secondary Accession #    Q05A74; Q8CBV2; Q99NB6 [Other Products]
 UniProt Related Accession #    Q9DBR7 [Other Products]
 Molecular Weight    Calculated MW: 115
Observed MW: 140
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 NCBI Official Full Name    MYPT1, partial
 NCBI Official Synonym Full Names    protein phosphatase 1, regulatory (inhibitor) subunit 12A
 NCBI Official Symbol    Ppp1r12a [Similar Products]
 NCBI Official Synonym Symbols   
Mypt1; AA792106; AV099298; D10Ertd625e; 1200015F06Rik; 5730577I22Rik
[Similar Products]
 NCBI Protein Information    protein phosphatase 1 regulatory subunit 12A
 UniProt Protein Name    Protein phosphatase 1 regulatory subunit 12A
 UniProt Synonym Protein Names   
Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1
 UniProt Gene Name    Ppp1r12a [Similar Products]
 UniProt Synonym Gene Names    Mypt1; Myosin phosphatase target subunit 1 [Similar Products]
 UniProt Entry Name    MYPT1_MOUSE
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 UniProt Comments for MYPT1    MYPT1: myosin phosphatase target subunit 1, a regulatory subunit of protein phosphatase 1. Also called the myosin-binding subunit of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. Four splice-variant isoforms have been described.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Cellular Component: A band; actin cytoskeleton; centrosome; contractile fiber; cytoplasm; focal adhesion; kinetochore; Z disc

Molecular Function: enzyme inhibitor activity; phosphatase regulator activity; phosphoprotein phosphatase activity; protein binding; protein kinase binding

Biological Process: centrosome organization and biogenesis; mitosis; negative regulation of catalytic activity; positive regulation of transcription from RNA polymerase II promoter; protein amino acid dephosphorylation; regulation of cell adhesion; regulation of nucleocytoplasmic transport; signal transduction
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 Research Articles on MYPT1    1. phosphorylation of MYPT1 T694, but not T852, mediates force maintenance in bladder smooth muscle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MYPT1 antibodyPathways associated with anti-MYPT1 antibody
 Reference Product  PubMed Publications
 Ppp1r14a antibody  >33 publications with MYPT1 and Ppp1r14a
 Rock2 antibody  >12 publications with MYPT1 and Rock2
 Rock1 antibody  >10 publications with MYPT1 and Rock1
 Plk1 antibody  >4 publications with MYPT1 and Plk1
 Prkg1 antibody  >1 publications with MYPT1 and Prkg1
 Myl9 antibody  >1 publications with MYPT1 and Myl9
 Ppp1cb antibody  >1 publications with MYPT1 and Ppp1cb
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Platelet Activation Pathway antibodies  Platelet Activation Pathway Diagram
Diseases associated with anti-MYPT1 antibodyOrgans/Tissues associated with anti-MYPT1 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >26 publications with MYPT1 and Cardiovascular Diseases
 Hypertension Antibodies  >24 publications with MYPT1 and Hypertension
 Disease Models, Animal Antibodies  >18 publications with MYPT1 and Disease Models, Animal
 Heart Diseases Antibodies  >7 publications with MYPT1 and Heart Diseases
 Necrosis Antibodies  >6 publications with MYPT1 and Necrosis
 Fibrosis Antibodies  >5 publications with MYPT1 and Fibrosis
 Inflammation Antibodies  >5 publications with MYPT1 and Inflammation
 Nervous System Diseases Antibodies  >5 publications with MYPT1 and Nervous System Diseases
 Hypertrophy Antibodies  >5 publications with MYPT1 and Hypertrophy
 Kidney Diseases Antibodies  >5 publications with MYPT1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >111 publications with MYPT1 and Muscle
 Blood Antibodies  >34 publications with MYPT1 and Blood
 Lung Antibodies  >20 publications with MYPT1 and Lung
 Heart Antibodies  >13 publications with MYPT1 and Heart
 Liver Antibodies  >10 publications with MYPT1 and Liver
 Intestine Antibodies  >10 publications with MYPT1 and Intestine
 Kidney Antibodies  >8 publications with MYPT1 and Kidney
 Brain Antibodies  >5 publications with MYPT1 and Brain
 Eye Antibodies  >4 publications with MYPT1 and Eye
 Bladder Antibodies  >4 publications with MYPT1 and Bladder
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