NP_115564.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,085 Da
NCBI Official Full Name
histone acetyltransferase KAT8 isoform 1
NCBI Official Synonym Full Names
lysine acetyltransferase 8
NCBI Protein Information
histone acetyltransferase KAT8
UniProt Protein Name
Histone acetyltransferase KAT8
UniProt Synonym Protein Names
Lysine acetyltransferase 8; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; hMOF
UniProt Synonym Gene Names
NCBI Summary for MYST1
This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for MYST1
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.
Product References and Citations for anti-MYST1 antibody
Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004). Neal K.C., Biochim. Biophys. Acta 1490:170-174(2000). Pardo P.S., J. Biol. Chem. 277:50860-50866(2002).
Research Articles on MYST1
Precautions
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Disclaimer
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Pathways associated with anti-MYST1 antibody
Diseases associated with anti-MYST1 antibody
Organs/Tissues associated with anti-MYST1 antibody
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