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anti-CCL4 antibody :: Rabbit anti-Mouse Macrophage Inflammatory Protein 1 beta Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175746
Testing Data
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Macrophage Inflammatory Protein 1 beta (CCL4), Polyclonal Antibody

 Also Known As   

Anti-Macrophage Inflammatory Protein 1 beta antibody

 Product Synonym Names    C-C motif chemokine 4; chemokine(C-C motif) ligand 4; MIP 1 beta antibody; Secreted protein G 26 antibody; ACT 2 antibody; ACT-2 antibody; ACT2 antibody; AT744.1 antibody; AT744.2 antibody; C C motif chemokine 4 antibody; C C motif chemokine 4 like antibody; CC chemokine ligand 4 antibody; CC chemokine ligand 4L1d2 antibody; CC chemokine ligand 4L2 antibody; CCL4 antibody; CCL4_HUMAN antibody; ccl4l 1 antibody; CCL4L antibody; CCL4L1 antibody; Chemokine(C C motif) ligand 4 antibody; Chemokine(C C motif) ligand 4 like 1 antibody; Chemokine(C C motif) ligand 4 like 1, telomeric antibody; Chemokine(C C motif) ligand 4 like 2 antibody; Chemokine CC Motif Ligand 4 antibody; G 26 antibody; G 26 T lymphocyte secreted protein antibody; G-26 T-lymphocyte-secreted protein antibody; HC21 antibody; LAG 1 antibody; LAG-1 antibody; LAG1 antibody; Lymphocyte activation gene 1 antibody; Lymphocyte activation gene 1 protein antibody; Macrophage inflammatory protein 1 beta antibody; Macrophage inflammatory protein 1-beta antibody; Macrophage inflammatory protein 1b2 antibody; MGC104418 antibody; MGC126025 antibody; MGC126026 antibody; MIP-1-beta antibody; MIP-1-beta(1-69) antibody; MIP-1-beta(3-69) antibody; MIP1 beta antibody; MIP1B antibody; MIP1B1 antibody; Monocyte adherence induced protein 5 alpha antibody; PAT 744 antibody; Protein H400 antibody; SCYA2 antibody; SCYA4 antibody; SCYA4L antibody; Secreted protein G26 antibody; SIS gamma antibody; SIS-gamma antibody; Small inducible cytokine A4(homologous to mouse Mip 1b) antibody; Small inducible cytokine A4 antibody; Small-inducible cytokine A4 antibody; T cell activation protein 2 antibody; T-cell activation protein 2 antibody
 Product Gene Name   

anti-CCL4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P14097
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Macrophage Inflammatory Protein 1 beta  (74-88aa CANPSEPWVTEYMSD).
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CCL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CCL4 antibody

   Description: Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Mouse.
Background: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al.(1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al.(1990): 17q21-q23 rather than 17q11-q21.
 Applications Tested/Suitable for anti-CCL4 antibody   

Western Blot (WB)

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 Testing Data of anti-CCL4 antibody    All lanes: Anti-CCL4, MBS175746
Lane 1: Mouse Spleen Tissue Lysate
Lane 2: Mouse Cardiac Muscle Tissue Lysate
Lane 3: Mouse Lung Tissue Lysate
Lane 4: Mouse Kidney Tissue Lysate
Lane 5: Mouse Skeletal Muscle Tissue Lysate
anti-CCL4 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CCL4. It may not necessarily be applicable to this product.
 NCBI GI #    1346534
 NCBI GeneID    20303
 NCBI Accession #    P14097.3 [Other Products]
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 UniProt Primary Accession #    P14097 [Other Products]
 UniProt Related Accession #    P14097 [Other Products]
 Molecular Weight    10,168 Da
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 NCBI Official Full Name    C-C motif chemokine 4
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 4
 NCBI Official Symbol    Ccl4 [Similar Products]
 NCBI Official Synonym Symbols   
Act-2; Mip1b; Scya4; MIP-1B; AT744.1
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 4; ACT2; SIS-gamma; MIP-1 beta; MIP-1-beta; immune activation protein 2; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta
 UniProt Protein Name    C-C motif chemokine 4
 UniProt Synonym Protein Names   
Immune activation protein 2; ACT-2; ACT2; Macrophage inflammatory protein 1-beta; MIP-1-beta; Protein H400; SIS-gamma; Small-inducible cytokine A4
 Protein Family    C-C motif chemokine
 UniProt Gene Name    Ccl4 [Similar Products]
 UniProt Synonym Gene Names    Mip1b; Scya4; ACT-2; ACT2; MIP-1-beta [Similar Products]
 UniProt Entry Name    CCL4_MOUSE
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 UniProt Comments for CCL4    CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: identical protein binding; protein binding; CCR1 chemokine receptor binding; chemokine activity; cytokine activity; CCR5 chemokine receptor binding

Biological Process: leukocyte chemotaxis; response to toxin; immune response; positive regulation of calcium-mediated signaling; positive regulation of tumor necrosis factor production; inflammatory response; chemotaxis; positive regulation of calcium ion transport; positive regulation of vascular permeability
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 Research Articles on CCL4    1. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CCL4 antibodyPathways associated with anti-CCL4 antibody
 Reference Product  PubMed Publications
 Ccl3 antibody  >1599 publications with CCL4 and Ccl3
 Ccl5 antibody  >985 publications with CCL4 and Ccl5
 Ccr5 antibody  >588 publications with CCL4 and Ccr5
 Ccr1 antibody  >198 publications with CCL4 and Ccr1
 Ccr2 antibody  >107 publications with CCL4 and Ccr2
 Cxcr3 antibody  >74 publications with CCL4 and Cxcr3
 Ccl7 antibody  >74 publications with CCL4 and Ccl7
 Ccr3 antibody  >71 publications with CCL4 and Ccr3
 Ccr8 antibody  >24 publications with CCL4 and Ccr8
 Ccl12 antibody  >12 publications with CCL4 and Ccl12
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with anti-CCL4 antibodyOrgans/Tissues associated with anti-CCL4 antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >2590 publications with CCL4 and Liver Diseases
 Poisoning Antibodies  >1967 publications with CCL4 and Poisoning
 Drug-Induced Liver Injury Antibodies  >1569 publications with CCL4 and Drug-Induced Liver Injury
 Disease Models, Animal Antibodies  >1266 publications with CCL4 and Disease Models, Animal
 Necrosis Antibodies  >1192 publications with CCL4 and Necrosis
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1163 publications with CCL4 and Drug-Related Side Effects and Adverse Reactions
 Liver Cirrhosis Antibodies  >1127 publications with CCL4 and Liver Cirrhosis
 Inflammation Antibodies  >1058 publications with CCL4 and Inflammation
 Fibrosis Antibodies  >899 publications with CCL4 and Fibrosis
 Fatty Liver Antibodies  >285 publications with CCL4 and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >293 publications with CCL4 and Bone Marrow
 Spleen Antibodies  >218 publications with CCL4 and Spleen
 Skin Antibodies  >135 publications with CCL4 and Skin
 Eye Antibodies  >61 publications with CCL4 and Eye
 Uncharacterized Tissue Antibodies  >1 publications with CCL4 and Uncharacterized Tissue
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