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anti-MIP5 antibody :: Rabbit anti-Human Macrophage Inflammatory Protein 5 (MIP5) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2003126 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $165 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $310 +1 FREE 8GB USB
1 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Macrophage Inflammatory Protein 5 (MIP5), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Macrophage Inflammatory Protein 5 (MIP5)

 Product Gene Name   

anti-MIP5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF- QFINDAETE LMMSKLPLEN PVVLNSFHFA ADCCTSYISQ SIPCSLMKSY FETSSECSKP GVIFLTKKGR QVCAKPSGPG VQDCMKKLKP YSI
 OMIM    U58914 mRNA
 3D Structure    ModBase 3D Structure for Q16663
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against MIP5. It has been selected for its ability to recognize MIP5 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant CCL15 (Gln22~Ile113) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2043857
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-MIP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MIP5 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-MIP5 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-MIP5 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-MIP5 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-MIP5 antibody    (Figure.DAB staining on IHC-P. Samples: Human Tissue)
anti-MIP5 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MIP5. It may not necessarily be applicable to this product.
 NCBI GI #    597709818
 NCBI GeneID    6359
 NCBI Accession #    NP_116741.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_032965.5 [Other Products]
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 UniProt Primary Accession #    Q16663 [Other Products]
 UniProt Secondary Accession #    Q9UM74; B2RU34; E1P651 [Other Products]
 UniProt Related Accession #    Q16663 [Other Products]
 Molecular Weight    12,248 Da
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 NCBI Official Full Name    C-C motif chemokine 15 preproprotein
 NCBI Official Synonym Full Names    C-C motif chemokine ligand 15
 NCBI Official Symbol    CCL15 [Similar Products]
 NCBI Official Synonym Symbols   
LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 15
 UniProt Protein Name    C-C motif chemokine 15
 UniProt Synonym Protein Names   
Chemokine CC-2; HCC-2
 UniProt Gene Name    CCL15 [Similar Products]
 UniProt Synonym Gene Names    MIP5; NCC3; SCYA15; HCC-2; LKN-1; MIP-5 [Similar Products]
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 NCBI Summary for MIP5    This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]
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 UniProt Comments for MIP5    CCL15: Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cell; extracellular space

Molecular Function: CCR chemokine receptor binding; chemoattractant activity; chemokine activity; heparin binding; receptor binding

Biological Process: cell-cell signaling; cellular calcium ion homeostasis; chemotaxis; G-protein coupled receptor signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive chemotaxis; positive regulation of GTPase activity; signal transduction
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 Research Articles on MIP5    1. CCL15 activation of CCR1 plays critical roles in hepatocellular carcinoma metastasis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MIP5 antibodyPathways associated with anti-MIP5 antibody
 Reference Product  PubMed Publications
 CCR1 antibody  >28 publications with MIP5 and CCR1
 CCR3 antibody  >11 publications with MIP5 and CCR3
 CCR2 antibody  >5 publications with MIP5 and CCR2
 CCR5 antibody  >4 publications with MIP5 and CCR5
 CCR6 antibody  >2 publications with MIP5 and CCR6
 CCR8 antibody  >1 publications with MIP5 and CCR8
 CCR7 antibody  >1 publications with MIP5 and CCR7
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-MIP5 antibodyOrgans/Tissues associated with anti-MIP5 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >22 publications with MIP5 and Inflammation
 Necrosis Antibodies  >7 publications with MIP5 and Necrosis
 Carcinoma Antibodies  >6 publications with MIP5 and Carcinoma
 Liver Neoplasms Antibodies  >5 publications with MIP5 and Liver Neoplasms
 Liver Diseases Antibodies  >5 publications with MIP5 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with MIP5 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >3 publications with MIP5 and Kidney Diseases
 Adenocarcinoma Antibodies  >3 publications with MIP5 and Adenocarcinoma
 Atherosclerosis Antibodies  >2 publications with MIP5 and Atherosclerosis
 Lung Neoplasms Antibodies  >2 publications with MIP5 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with MIP5 and Liver
 Lung Antibodies  >6 publications with MIP5 and Lung
 Kidney Antibodies  >4 publications with MIP5 and Kidney
 Intestine Antibodies  >3 publications with MIP5 and Intestine
 Brain Antibodies  >2 publications with MIP5 and Brain
 Ascites Antibodies  >1 publications with MIP5 and Ascites
 Prostate Antibodies  >1 publications with MIP5 and Prostate
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