NP_032946.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
bone marrow proteoglycan
NCBI Official Synonym Full Names
proteoglycan 2, bone marrow
NCBI Protein Information
bone marrow proteoglycan
UniProt Protein Name
Bone marrow proteoglycan
UniProt Synonym Protein Names
Proteoglycan 2
UniProt Synonym Gene Names
UniProt Comments for MBP
PRG2: Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
Protein type: Secreted; Secreted, signal peptide; Vesicle
Chromosomal Location of Human Ortholog: 2 D|2 49.45 cM
Molecular Function: carbohydrate binding
Biological Process: defense response to bacterium; defense response to nematode; immune response; immune system process; negative regulation of interleukin-10 production; positive regulation of interleukin-4 production; regulation of cytokine biosynthetic process
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Products associated with anti-MBP antibody
Pathways associated with anti-MBP antibody
Diseases associated with anti-MBP antibody
Organs/Tissues associated with anti-MBP antibody
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