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Product Name
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Mcp10/Mcp9 (Cma2), Polyclonal Antibody
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Also Known As
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Goat anti-Mcp10/Mcp9 Antibody
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Product Synonym Names
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Cma2; Chymase 2, mast cell; Mast cell protease 10; Mcp10; Cma2 antibody; Chymase 2; mast cell antibody; Mast cell protease 10 antibody; Mcp10 antibody; Mcp10 / Mcp9
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Product Gene Name
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[Similar Products]
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Product Synonym Gene Name
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Mcp10; Mcp9
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[Similar Products]
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Antibody/Peptide Pairs
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Mcp10 / Mcp9 peptide (MBS425988) is used for blocking the activity of Mcp10/Mcp9 antibody (MBS421981)
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Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
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CKIFKHYKDS LQ
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Clonality
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Polyclonal
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Host
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Goat
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Species Reactivity
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Expected from sequence similarity: Mouse
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Purity/Purification
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Form/Format
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Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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Concentration
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100ug specific antibody in 200ul (lot specific)
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Immunogen
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Peptide with sequence CKIFKHYKDSLQ, from the intenal region of the protein sequence according to NP_001019885.1; NP_034912.3.
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Epitope
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Internal region
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Note
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Mcp 10 and Mcp 9 (GeneID 545055) are almost identical in their protein sequence. No cross-reactivity expected with the similar Mcp4.
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Preparation and Storage
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Aliquot and store at -20 degree C. Minimize freezing and thawing.
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ISO Certification
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Manufactured in an ISO 9001:2015 Certified Laboratory.
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Other Notes
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Small volumes of anti-Cma2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-Cma2 antibody
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Peptide ELISA (EIA)
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Application Notes for anti-Cma2 antibody
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Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Preliminary experiments gave an approx 49kDa band in Human Skeletal Muscle lysates after 0. 02ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 26.9kDa according to NP_001019885.1 and NP_034912.3. The 49kDa band was successfully blocked by incubation with the immunizing peptide.
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NCBI/Uniprot data below describe general gene information for Cma2. It may not necessarily be applicable to this product. |
NCBI GI #
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67010053
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NCBI GeneID
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545055
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NCBI Accession #
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NP_001019885.1
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[Other Products]
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NCBI Related Accession #
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NP_034912.3
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[Other Products]
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NCBI GenBank Nucleotide #
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NM_001024714.2
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[Other Products]
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NCBI Official Full Name
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mast cell protease 10
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NCBI Official Synonym Full Names
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chymase 2, mast cell
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NCBI Official Symbol
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Cma2
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[Similar Products]
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NCBI Official Synonym Symbols
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Mcp10
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[Similar Products]
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NCBI Protein Information
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mast cell protease 10
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Research Articles on Cma2
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1. mast cell chymase and CPA have key roles in both the generation and degradation of Ang II
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Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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