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anti-TIMP4 antibody :: Rabbit anti-Human Metalloproteinase inhibitor 4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489868 anti-TIMP4 antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metalloproteinase inhibitor 4 (TIMP4), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-Human Metalloproteinase inhibitor 4 polyclonal Antibody, Biotin conjugated

 Product Synonym Names    Tissue inhibitor of metalloproteinases 4; TIMP4
 Product Gene Name   

anti-TIMP4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601915
 3D Structure    ModBase 3D Structure for Q99727
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Biotin
 Immunogen    Recombinant Human Metalloproteinase inhibitor 4 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9375 / sc-30076
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TIMP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TIMP4 antibody

   Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
 Applications Tested/Suitable for anti-TIMP4 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for TIMP4. It may not necessarily be applicable to this product.
 NCBI GI #    4507515
 NCBI GeneID    7079
 NCBI Accession #    NP_003247.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003256.3 [Other Products]
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 UniProt Primary Accession #    Q99727 [Other Products]
 UniProt Secondary Accession #    B2R7K6 [Other Products]
 UniProt Related Accession #    Q99727 [Other Products]
 Molecular Weight    25,503 Da [Similar Products]
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 NCBI Official Full Name    metalloproteinase inhibitor 4
 NCBI Official Synonym Full Names    TIMP metallopeptidase inhibitor 4
 NCBI Official Symbol    TIMP4 [Similar Products]
 NCBI Protein Information    metalloproteinase inhibitor 4
 UniProt Protein Name    Metalloproteinase inhibitor 4
 UniProt Synonym Protein Names   
Tissue inhibitor of metalloproteinases 4; TIMP-4
 Protein Family    Metalloproteinase inhibitor
 UniProt Gene Name    TIMP4 [Similar Products]
 UniProt Synonym Gene Names    TIMP-4 [Similar Products]
 UniProt Entry Name    TIMP4_HUMAN
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 NCBI Summary for TIMP4    This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TIMP4    TIMP4: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. Belongs to the protease inhibitor I35 (TIMP) family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: extracellular space; proteinaceous extracellular matrix; sarcomere

Molecular Function: metal ion binding; metalloendopeptidase inhibitor activity; protease binding

Biological Process: central nervous system development; negative regulation of membrane protein ectodomain proteolysis; negative regulation of metalloenzyme activity; Notch signaling pathway; ovulation cycle; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to organic substance; response to peptide hormone stimulus
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 Research Articles on TIMP4    1. Upregulation of plasma TIMP-4 might contribute to PIH [pregnancy-induced hypertension] processes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TIMP4 antibodyPathways associated with anti-TIMP4 antibody
 Reference Product  PubMed Publications
 MMP2 antibody  >25 publications with TIMP4 and MMP2
 MMP9 antibody  >22 publications with TIMP4 and MMP9
 MMP3 antibody  >13 publications with TIMP4 and MMP3
 MMP13 antibody  >11 publications with TIMP4 and MMP13
 MMP8 antibody  >6 publications with TIMP4 and MMP8
 MMP14 antibody  >6 publications with TIMP4 and MMP14
 MMP7 antibody  >5 publications with TIMP4 and MMP7
 MMP26 antibody  >1 publications with TIMP4 and MMP26
 Products by Pathway  Pathway Diagram
 Matrix Metalloproteinases Pathway antibodies  Matrix Metalloproteinases Pathway Diagram
Diseases associated with anti-TIMP4 antibodyOrgans/Tissues associated with anti-TIMP4 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >21 publications with TIMP4 and Cardiovascular Diseases
 Inflammation Antibodies  >14 publications with TIMP4 and Inflammation
 Fibrosis Antibodies  >9 publications with TIMP4 and Fibrosis
 Nervous System Diseases Antibodies  >9 publications with TIMP4 and Nervous System Diseases
 Disease Models, Animal Antibodies  >8 publications with TIMP4 and Disease Models, Animal
 Necrosis Antibodies  >6 publications with TIMP4 and Necrosis
 Atherosclerosis Antibodies  >5 publications with TIMP4 and Atherosclerosis
 Hypertrophy Antibodies  >5 publications with TIMP4 and Hypertrophy
 Lung Neoplasms Antibodies  >4 publications with TIMP4 and Lung Neoplasms
 Breast Neoplasms Antibodies  >4 publications with TIMP4 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >17 publications with TIMP4 and Heart
 Vascular Antibodies  >14 publications with TIMP4 and Vascular
 Lung Antibodies  >11 publications with TIMP4 and Lung
 Brain Antibodies  >8 publications with TIMP4 and Brain
 Embryonic Tissue Antibodies  >7 publications with TIMP4 and Embryonic Tissue
 Bone Antibodies  >5 publications with TIMP4 and Bone
 Connective Tissue Antibodies  >5 publications with TIMP4 and Connective Tissue
 Eye Antibodies  >3 publications with TIMP4 and Eye
 Skin Antibodies  >2 publications with TIMP4 and Skin
 Liver Antibodies  >2 publications with TIMP4 and Liver
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