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anti-MT2 antibody :: Rabbit anti-Human Metallothionein 2 (MT2) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2003248 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $220 +1 FREE 8GB USB
0.2 mg  /  $320 +1 FREE 8GB USB
1 mg  /  $760 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metallothionein 2 (MT2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Metallothionein 2 (MT2)

 Product Gene Name   

anti-MT2 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
Biotin Conjugated Antibody: Metallothionein 2 (MT2) (MBS2003161)
 Matching Pairs    Antibody: Metallothionein 2 (MT2) (MBS2003248)
Antigen: Metallothionein 2 (MT2) (MBS2012291)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
FITC Conjugated Antibody: Metallothionein 2 (MT2) (MBS2014002)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
APC-CY7 Conjugated Antibody: Metallothionein 2 (MT2) (MBS2060020)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
PE Conjugated Antibody: Metallothionein 2 (MT2) (MBS2060021)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
APC-CY7 Conjugated Antibody: Metallothionein 2 (MT2) (MBS2060022)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
Cy3 Conjugated Antibody: Metallothionein 2 (MT2) (MBS2060023)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
HRP Conjugated Antibody: Metallothionein 2 (MT2) (MBS2060024)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Metallothionein 2 (MT2) (MBS2003248)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and S-tag and its sequence is listed below.
MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF- DPNCSCAAG DSCTCAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCIC KGASDKCSCC A
 OMIM    J00271 Genomic DNA
 3D Structure    ModBase 3D Structure for P02795
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against MT2. It has been selected for its ability to recognize MT2 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant MT2 (Asp2~Ala61) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2060022
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-MT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MT2 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-MT2 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-MT2 antibody    (Figure. Western Blot; Sample: Recombinant MT2, Human.)
anti-MT2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-MT2 antibody    (Used in DAB staining on formalin fixed paraffin- embedded rectum tissue)
anti-MT2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MT2. It may not necessarily be applicable to this product.
 NCBI GI #    5174764
 NCBI GeneID    4502
 NCBI Accession #    NP_005944.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005953.4 [Other Products]
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 UniProt Primary Accession #    P02795 [Other Products]
 UniProt Secondary Accession #    Q14823; Q2HXR9; Q53XT9 [Other Products]
 UniProt Related Accession #    P02795 [Other Products]
 Molecular Weight    6,042 Da
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 NCBI Official Full Name    metallothionein-2
 NCBI Official Synonym Full Names    metallothionein 2A
 NCBI Official Symbol    MT2A [Similar Products]
 NCBI Official Synonym Symbols   
MT2; MT-2; MT-II
[Similar Products]
 NCBI Protein Information    metallothionein-2
 UniProt Protein Name    Metallothionein-2
 UniProt Synonym Protein Names   
Metallothionein-2A; Metallothionein-II; MT-II
 Protein Family    Metallothionein
 UniProt Gene Name    MT2A [Similar Products]
 UniProt Synonym Gene Names    CES1; MT2; MT-2; MT-II [Similar Products]
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 NCBI Summary for MT2    This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
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 UniProt Comments for MT2    MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: cytoplasm; cytosol; nucleus; perinuclear region of cytoplasm

Molecular Function: drug binding; protein binding; zinc ion binding

Biological Process: cellular copper ion homeostasis; negative regulation of growth; response to metal ion
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 Research Articles on MT2    1. We found a significant association of SNP rs28366003 at MT2A gene with susceptibility to the dry form of AMD in a Northern Spanish population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MT2 antibodyPathways associated with anti-MT2 antibody
 Reference Product  PubMed Publications
 MT1G antibody  >10 publications with MT2 and MT1G
 MT1H antibody  >9 publications with MT2 and MT1H
 HIPK2 antibody  >1 publications with MT2 and HIPK2
 SPINK7 antibody  >1 publications with MT2 and SPINK7
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
Diseases associated with anti-MT2 antibodyOrgans/Tissues associated with anti-MT2 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >18 publications with MT2 and Carcinoma
 Inflammation Antibodies  >17 publications with MT2 and Inflammation
 Nervous System Diseases Antibodies  >9 publications with MT2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >8 publications with MT2 and Cardiovascular Diseases
 Prostatic Neoplasms Antibodies  >7 publications with MT2 and Prostatic Neoplasms
 Immune System Diseases Antibodies  >6 publications with MT2 and Immune System Diseases
 Necrosis Antibodies  >5 publications with MT2 and Necrosis
 Atherosclerosis Antibodies  >5 publications with MT2 and Atherosclerosis
 Stomach Neoplasms Antibodies  >5 publications with MT2 and Stomach Neoplasms
 Liver Diseases Antibodies  >5 publications with MT2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >29 publications with MT2 and Blood
 Liver Antibodies  >15 publications with MT2 and Liver
 Brain Antibodies  >10 publications with MT2 and Brain
 Prostate Antibodies  >9 publications with MT2 and Prostate
 Lung Antibodies  >8 publications with MT2 and Lung
 Muscle Antibodies  >7 publications with MT2 and Muscle
 Vascular Antibodies  >6 publications with MT2 and Vascular
 Heart Antibodies  >6 publications with MT2 and Heart
 Kidney Antibodies  >6 publications with MT2 and Kidney
 Intestine Antibodies  >6 publications with MT2 and Intestine
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