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anti-MT3 antibody :: Rabbit anti-Human Metallothionein 3 (MT3) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2013101 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-MT3 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metallothionein 3 (MT3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Biotin-Linked Antibody to Metallothionein 3 (MT3)

 Product Gene Name   

anti-MT3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 16; NC_000016.9 (56623267..56625000). Location: 16q13
 OMIM    139255
 3D Structure    ModBase 3D Structure for P25713
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
 Concentration    200ug/ml (lot specific)
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 Source    Antibody labeling
 Label    Biotin
 Traits    Liquid
 Immunogen    Recombinant MT3 (Met1~Gln68) expressed in E.coli
    
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-MT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MT3 antibody    Biotin Antibody
 Applications Tested/Suitable for anti-MT3 antibody   

WB; IHC; ICC.

 Application Notes for anti-MT3 antibody    Western blotting: 0.5-2g/mL
Immunocytochemistry in formalin fixed cells: 5-20g/mL
Immunohistochemistry in formalin fixed frozen section: 5-20g/mL
Immunohistochemistry in paraffin section: 5-20g/mL

Optimal working dilutions must be determined by end user
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NCBI/Uniprot data below describe general gene information for MT3. It may not necessarily be applicable to this product.
 NCBI GI #    15341818
 NCBI GeneID    4504
 NCBI Accession #    AAH13081.1 [Other Products]
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 UniProt Primary Accession #    P25713 [Other Products]
 UniProt Secondary Accession #    Q2V574 [Other Products]
 UniProt Related Accession #    P25713 [Other Products]
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 NCBI Official Full Name    Metallothionein 3
 NCBI Official Synonym Full Names    metallothionein 3
 NCBI Official Symbol    MT3 [Similar Products]
 NCBI Official Synonym Symbols   
GIF; GIFB; GRIF; ZnMT3
[Similar Products]
 NCBI Protein Information    metallothionein-3; MT-3; MT-III; metallothionein-III; growth inhibitory factor; metallothionein 3 (growth inhibitory factor (neurotrophic))
 UniProt Protein Name    Metallothionein-3
 UniProt Synonym Protein Names   
GIFB; GIF; Growth inhibitory factor; Metallothionein-III
 Protein Family    Metallothionein
 UniProt Gene Name    MT3 [Similar Products]
 UniProt Synonym Gene Names    MT-3; GIF; MT-III [Similar Products]
 UniProt Entry Name    MT3_HUMAN
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 UniProt Comments for MT3    MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family.

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; inclusion body; intracellular

Molecular Function: antioxidant activity; protein binding; copper ion binding; zinc ion binding; caspase inhibitor activity; drug binding; cadmium ion binding; protein kinase activator activity

Biological Process: positive regulation of catalytic activity; negative regulation of autophagy; removal of superoxide radicals; positive regulation of transcription, DNA-dependent; negative regulation of caspase activity; negative regulation of axon extension; positive regulation of vascular endothelial growth factor receptor signaling pathway; zinc ion homeostasis; cadmium ion homeostasis; cellular lipid catabolic process; histone modification; protein kinase B signaling cascade; negative regulation of neuron apoptosis; cholesterol catabolic process; regulation of response to food; protein stabilization; cellular zinc ion homeostasis; activation of protein kinase B; zinc ion transport; regulation of protein amino acid glycosylation; leptin-mediated signaling pathway; astrocyte development; cell proliferation; cellular metal ion homeostasis; protein import into nucleus, translocation; negative regulation of oxidoreductase activity; response to hypoxia; energy reserve metabolic process; positive regulation of protein amino acid phosphorylation; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
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 Research Articles on MT3    1. The experiments indicate that MT3 is an androgen-upregulated gene, and promotes tumorigenesis of prostate carcinoma cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MT3 antibodyDiseases associated with anti-MT3 antibody
 Reference Product  PubMed Publications
 CD4 antibody  >1 publications with MT3 and CD4
 TTR antibody  >1 publications with MT3 and TTR
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >76 publications with MT3 and Neoplasms
 Immune System Diseases Antibodies  >26 publications with MT3 and Immune System Diseases
 Nervous System Diseases Antibodies  >25 publications with MT3 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >20 publications with MT3 and Neoplasm Metastasis
 Skin Diseases Antibodies  >17 publications with MT3 and Skin Diseases
 Brain Diseases Antibodies  >15 publications with MT3 and Brain Diseases
 Breast Neoplasms Antibodies  >12 publications with MT3 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >10 publications with MT3 and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >9 publications with MT3 and Lung Neoplasms
 Lung Diseases Antibodies  >9 publications with MT3 and Lung Diseases
Organs/Tissues associated with anti-MT3 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >61 publications with MT3 and Brain
 Connective Tissue Antibodies  >12 publications with MT3 and Connective Tissue
 Eye Antibodies  >11 publications with MT3 and Eye
 Ovary Antibodies  >8 publications with MT3 and Ovary
 Prostate Antibodies  >7 publications with MT3 and Prostate
 Spinal Cord Antibodies  >4 publications with MT3 and Spinal Cord
 Testis Antibodies  >1 publications with MT3 and Testis
 Adrenal Gland Antibodies  >1 publications with MT3 and Adrenal Gland
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